Gene description for INTS1
Gene name integrator complex subunit 1
Gene symbol INTS1
Other names/aliases INT1
NET28
Species Homo sapiens
 Database cross references - INTS1
ExoCarta ExoCarta_26173
Entrez Gene 26173
HGNC 24555
MIM 611345
UniProt Q8N201  
 INTS1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for INTS1
Biological Process
    U2 snRNA 3'-end processing GO:0034474 IEA
    negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 IEA
    inner cell mass cell proliferation GO:0001833 IEA
    snRNA processing GO:0016180 IDA
Subcellular Localization
    membrane GO:0016020 IDA
    integrator complex GO:0032039 IDA
    nuclear membrane GO:0031965 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified INTS1 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for INTS1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which INTS1 is involved
No pathways found





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