Gene description for MAD2L2
Gene name	MAD2 mitotic arrest deficient-like 2 (yeast)
Gene symbol	MAD2L2
Other names/aliases	MAD2B POLZ2 REV7
Species	Homo sapiens
Database cross references - MAD2L2
ExoCarta	ExoCarta_10459
Vesiclepedia	VP_10459
Entrez Gene	10459
HGNC	6764
MIM	604094
UniProt	Q9UI95
MAD2L2 identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for MAD2L2

Molecular Function     JUN kinase binding GO:0008432 IDA     protein binding GO:0005515 IPI     RNA polymerase II activating transcription factor binding GO:0001102 IPI Biological Process     regulation of cell growth GO:0001558 IGI     negative regulation of APC-Cdc20 complex activity GO:0060564 IDA     positive regulation of peptidyl-serine phosphorylation GO:0033138 IDA     negative regulation of cell-cell adhesion mediated by cadherin GO:2000048 IMP     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IDA     negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433 IDA     negative regulation of canonical Wnt signaling pathway GO:0090090 IMP     negative regulation of transcription regulatory region DNA binding GO:2000678 IMP     translesion synthesis GO:0019985 TAS     double-strand break repair GO:0006302 IGI     error-prone translesion synthesis GO:0042276 TAS     cell division GO:0051301 IEA     negative regulation of epithelial to mesenchymal transition GO:0010719 IMP     transcription, DNA-templated GO:0006351 IEA     DNA repair GO:0006281 TAS     DNA damage response, signal transduction resulting in transcription GO:0042772 IDA     negative regulation of protein catabolic process GO:0042177 IDA     negative regulation of transcription by competitive promoter binding GO:0010944 IMP     actin filament organization GO:0007015 IMP     mitotic nuclear division GO:0007067 IEA     positive regulation of transcription, DNA-templated GO:0045893 IMP     mitotic spindle assembly checkpoint GO:0007094 TAS Subcellular Localization     cytoplasm GO:0005737 IEA     nucleoplasm GO:0005654 TAS     zeta DNA polymerase complex GO:0016035 IDA     spindle GO:0005819 IDA     nucleus GO:0005634 IDA     anaphase-promoting complex GO:0005680 IDA