Gene description for YY1AP1
Gene name YY1 associated protein 1
Gene symbol YY1AP1
Other names/aliases HCCA1
HCCA2
YAP
YY1AP
Species Homo sapiens
 Database cross references - YY1AP1
ExoCarta ExoCarta_55249
Entrez Gene 55249
HGNC 30935
MIM 607860
UniProt Q9H869  
 YY1AP1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for YY1AP1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    regulation of transcription, DNA-templated GO:0006355 IEA
    regulation of cell cycle GO:0051726 IDA
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified YY1AP1 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for YY1AP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EWSR1 2130
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which YY1AP1 is involved
No pathways found





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