Gene description for YY1AP1
Gene name YY1 associated protein 1
Gene symbol YY1AP1
Other names/aliases HCCA1
HCCA2
YAP
YY1AP
Species Homo sapiens
 Database cross references - YY1AP1
ExoCarta ExoCarta_55249
Vesiclepedia VP_55249
Entrez Gene 55249
HGNC 30935
MIM 607860
UniProt Q9H869  
 YY1AP1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for YY1AP1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    cell population proliferation GO:0008283 IMP
    cell differentiation GO:0030154 IMP
    regulation of cell cycle GO:0051726 IDA
    regulation of cell cycle GO:0051726 IMP
Subcellular Localization
    fibrillar center GO:0001650 IDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 IEA
    Ino80 complex GO:0031011 IDA
 Experiment description of studies that identified YY1AP1 in exosomes
1
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for YY1AP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TRIM52  
Affinity Capture-MS Homo sapiens
2 ZMYM4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 FTL 2512
Affinity Capture-MS Homo sapiens
4 ATXN1 6310
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
5 H2AFJ 55766
Affinity Capture-MS Homo sapiens
6 PRM2  
Affinity Capture-MS Homo sapiens
7 CLEC3A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 FEV  
Proximity Label-MS Homo sapiens
9 PRR20A  
Affinity Capture-MS Homo sapiens
10 MAPK8IP2  
Two-hybrid Homo sapiens
11 ZNF579  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 ATXN1L  
Two-hybrid Homo sapiens
13 NFYC 4802
Proximity Label-MS Homo sapiens
14 MEN1 4221
Affinity Capture-MS Homo sapiens
15 SMURF1 57154
Affinity Capture-MS Homo sapiens
16 VHL  
Two-hybrid Homo sapiens
17 FOXL1  
Proximity Label-MS Homo sapiens
18 MAGEA9  
Affinity Capture-MS Homo sapiens
19 PRPS2 5634
Affinity Capture-MS Homo sapiens
20 DCAF12 25853
Affinity Capture-MS Homo sapiens
21 CDC16 8881
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 ZNF496  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 PRR20E  
Affinity Capture-MS Homo sapiens
24 SS18L2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 BAG1 573
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 CEBPZ  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 ZNF524  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 CHCHD2  
Affinity Capture-MS Homo sapiens
29 B3GALNT2 148789
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 ZNF653  
Affinity Capture-MS Homo sapiens
31 GBE1 2632
Affinity Capture-MS Homo sapiens
32 DDX54 79039
Affinity Capture-MS Homo sapiens
33 ZFAT  
Two-hybrid Homo sapiens
34 FBL 2091
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 MAPK14 1432
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
36 PRKAB2 5565
Two-hybrid Homo sapiens
37 MAD2L2 10459
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
38 EWSR1 2130
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
39 NEUROG3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 HIC2 23119
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 LUC7L 55692
Affinity Capture-MS Homo sapiens
42 FHL2 2274
Affinity Capture-MS Homo sapiens
43 MDM2  
Two-hybrid Homo sapiens
44 PIPSL 266971
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which YY1AP1 is involved
No pathways found





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