Gene description for B3GALNT2
Gene name beta-1,3-N-acetylgalactosaminyltransferase 2
Gene symbol B3GALNT2
Other names/aliases B3GalNAc-T2
MDDGA11
Species Homo sapiens
 Database cross references - B3GALNT2
ExoCarta ExoCarta_148789
Vesiclepedia VP_148789
Entrez Gene 148789
HGNC 28596
MIM 610194
UniProt Q8NCR0  
 B3GALNT2 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for B3GALNT2
Molecular Function
    acetylglucosaminyltransferase activity GO:0008375 IDA
    acetylgalactosaminyltransferase activity GO:0008376 IDA
    galactosyltransferase activity GO:0008378 IEA
Biological Process
    protein O-linked glycosylation GO:0006493 IDA
    protein glycosylation GO:0006486 IMP
Subcellular Localization
    endoplasmic reticulum GO:0005783 IDA
    Golgi membrane GO:0000139 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified B3GALNT2 in exosomes
1
Experiment ID 235
MISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Enriched markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for B3GALNT2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which B3GALNT2 is involved
No pathways found





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