Gene description for GFRA3
Gene name GDNF family receptor alpha 3
Gene symbol GFRA3
Other names/aliases GDNFR3
Species Homo sapiens
 Database cross references - GFRA3
ExoCarta ExoCarta_2676
Vesiclepedia VP_2676
Entrez Gene 2676
HGNC 4245
MIM 605710
UniProt O60609  
 GFRA3 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for GFRA3
Molecular Function
    receptor binding GO:0005102 TAS
    axon guidance receptor activity GO:0008046 IEA
Biological Process
    signal transduction GO:0007165 TAS
    sympathetic nervous system development GO:0048485 IEA
    axon guidance GO:0007411 IEA
    neuron migration GO:0001764 IEA
    nervous system development GO:0007399 TAS
    peripheral nervous system development GO:0007422 TAS
Subcellular Localization
    plasma membrane GO:0005886 IDA
    cytoplasm GO:0005737 IDA
    anchored component of membrane GO:0031225 IEA
    external side of plasma membrane GO:0009897 IEA
    intracellular membrane-bounded organelle GO:0043231 IDA
    extrinsic component of membrane GO:0019898 TAS
 Experiment description of studies that identified GFRA3 in exosomes
1
Experiment ID 126
MISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Enriched markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Antibody array
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for GFRA3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ARTN  
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which GFRA3 is involved
No pathways found





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