Gene description for CHST8
Gene name carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
Gene symbol CHST8
Other names/aliases GALNAC4ST1
GalNAc4ST
PSS3
Species Homo sapiens
 Database cross references - CHST8
ExoCarta ExoCarta_64377
Entrez Gene 64377
HGNC 15993
MIM 610190
UniProt Q9H2A9  
 CHST8 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for CHST8
Molecular Function
    N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 IDA
Biological Process
    sulfur compound metabolic process GO:0006790 IDA
    hormone biosynthetic process GO:0042446 IEP
    proteoglycan biosynthetic process GO:0030166 IDA
    carbohydrate biosynthetic process GO:0016051 IEA
    central nervous system development GO:0007417 NAS
Subcellular Localization
    Golgi membrane GO:0000139 IEA
    integral component of membrane GO:0016021 NAS
 Experiment description of studies that identified CHST8 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for CHST8
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CHST8 is involved
No pathways found





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