Gene description for MOXD1
Gene name monooxygenase, DBH-like 1
Gene symbol MOXD1
Other names/aliases MOX
PRO5780
dJ248E1.1
Species Homo sapiens
 Database cross references - MOXD1
ExoCarta ExoCarta_26002
Entrez Gene 26002
HGNC 21063
MIM 609000
UniProt Q6UVY6  
 MOXD1 identified in exosomes derived from the following tissue/cell type
Melanoma cells 25950383    
 Gene ontology annotations for MOXD1
Molecular Function
    protein binding GO:0005515 IPI
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen GO:0016715 IEA
    copper ion binding GO:0005507 IEA
Biological Process
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IDA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified MOXD1 in exosomes
1
Experiment ID 259
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
FLOT1
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for MOXD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MOXD1 is involved
No pathways found





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