Gene description for SIAE
Gene name sialic acid acetylesterase
Gene symbol SIAE
Other names/aliases AIS6
CSE-C
CSEC
LSE
YSG2
Species Homo sapiens
 Database cross references - SIAE
ExoCarta ExoCarta_54414
Entrez Gene 54414
HGNC 18187
MIM 610079
UniProt Q9HAT2  
 SIAE identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for SIAE
Molecular Function
    sialate O-acetylesterase activity GO:0001681 IDA
Biological Process
    carbohydrate metabolic process GO:0005975 IDA
    regulation of immune system process GO:0002682 IMP
Subcellular Localization
    lysosome GO:0005764 IEA
    extracellular exosome GO:0070062 IDA
    extracellular space GO:0005615 IDA
 Experiment description of studies that identified SIAE in exosomes
1
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SIAE
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SIAE is involved
No pathways found





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