Gene description for ERAP1
Gene name	endoplasmic reticulum aminopeptidase 1
Gene symbol	ERAP1
Other names/aliases	A-LAP ALAP APPILS ARTS-1 ARTS1 ERAAP ERAAP1 PILS-AP PILSAP
Species	Homo sapiens
Database cross references - ERAP1
ExoCarta	ExoCarta_51752
Entrez Gene	51752
HGNC	18173
MIM	606832
UniProt	Q9NZ08
ERAP1 identified in exosomes derived from the following tissue/cell type
Saliva	19199708
Thymus	23844026

Gene ontology annotations for ERAP1

Molecular Function     interleukin-6 receptor binding GO:0005138 IPI     metalloexopeptidase activity GO:0008235 IDA     interleukin-1, Type II receptor binding GO:0005151 TAS     zinc ion binding GO:0008270 NAS     protein binding GO:0005515 IPI     aminopeptidase activity GO:0004177 IDA Biological Process     angiogenesis GO:0001525 TAS     response to bacterium GO:0009617 NAS     regulation of blood pressure GO:0008217 TAS     positive regulation of angiogenesis GO:0045766 IEA     antigen processing and presentation of endogenous peptide antigen via MHC class I GO:0019885 TAS     membrane protein ectodomain proteolysis GO:0006509 IDA     fat cell differentiation GO:0045444 NAS     antigen processing and presentation of peptide antigen via MHC class I GO:0002474 TAS     regulation of innate immune response GO:0045088 NAS Subcellular Localization     extracellular exosome GO:0070062 IDA     endoplasmic reticulum lumen GO:0005788 TAS     cytosol GO:0005829 NAS     endoplasmic reticulum membrane GO:0005789 IEA     integral component of membrane GO:0016021 NAS     endoplasmic reticulum GO:0005783 NAS     extracellular region GO:0005576 IDA     membrane GO:0016020 IDA     extracellular space GO:0005615 IDA