Gene description for APOL2
Gene name apolipoprotein L, 2
Gene symbol APOL2
Other names/aliases APOL-II
APOL3
Species Homo sapiens
 Database cross references - APOL2
ExoCarta ExoCarta_23780
Entrez Gene 23780
HGNC 619
MIM 607252
UniProt Q9BQE5  
 APOL2 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for APOL2
Molecular Function
    receptor binding GO:0005102 NAS
    high-density lipoprotein particle binding GO:0008035 NAS
    lipid binding GO:0008289 NAS
Biological Process
    cholesterol metabolic process GO:0008203 NAS
    maternal process involved in female pregnancy GO:0060135 NAS
    acute-phase response GO:0006953 NAS
    lipid transport GO:0006869 NAS
    lipid metabolic process GO:0006629 NAS
    lipoprotein metabolic process GO:0042157 IEA
    multicellular organismal development GO:0007275 NAS
Subcellular Localization
    extracellular region GO:0005576 IEA
    membrane GO:0016020 IDA
    endoplasmic reticulum membrane GO:0005789 NAS
 Experiment description of studies that identified APOL2 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for APOL2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which APOL2 is involved
No pathways found





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