Gene description for MTCH2
Gene name mitochondrial carrier 2
Gene symbol MTCH2
Other names/aliases HSPC032
MIMP
SLC25A50
Species Homo sapiens
 Database cross references - MTCH2
ExoCarta ExoCarta_23788
Entrez Gene 23788
HGNC 17587
MIM 613221
UniProt Q9Y6C9  
 MTCH2 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 17956143    
 Gene ontology annotations for MTCH2
Biological Process
    regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 IEA
    protein localization to mitochondrion GO:0070585 IMP
    hepatocyte apoptotic process GO:0097284 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 IDA
    mitochondrial outer membrane GO:0005741 IEA
    mitochondrial inner membrane GO:0005743 IEA
    nucleus GO:0005634 IDA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified MTCH2 in exosomes
1
Experiment ID 20
ISEV standards
EM
EV Biophysical techniques
HSP90
EV Cytosolic markers
CD63|CD81|LAMP1
EV Membrane markers
GOLGA2|cytochrome c
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for MTCH2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MTCH2 is involved
No pathways found





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