Gene description for MTFR1L
Gene name mitochondrial fission regulator 1-like
Gene symbol MTFR1L
Other names/aliases FAM54B
HYST1888
MST116
MSTP116
Species Homo sapiens
 Database cross references - MTFR1L
ExoCarta ExoCarta_56181
Vesiclepedia VP_56181
Entrez Gene 56181
HGNC 28836
UniProt Q9H019  
 MTFR1L identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for MTFR1L
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    mitochondrial fission GO:0000266 IBA
    aerobic respiration GO:0009060 IBA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrial outer membrane GO:0005741 IEA
 Experiment description of studies that identified MTFR1L in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MTFR1L
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TACR3  
Affinity Capture-MS Homo sapiens
2 PFDN1 5201
Affinity Capture-MS Homo sapiens
3 PHB2 11331
Proximity Label-MS Homo sapiens
4 C1orf101  
Affinity Capture-MS Homo sapiens
5 S100P 6286
Affinity Capture-MS Homo sapiens
6 MTCH1 23787
Proximity Label-MS Homo sapiens
7 PRKY  
Affinity Capture-MS Homo sapiens
8 FAS 355
Proximity Label-MS Homo sapiens
9 CUL3 8452
Affinity Capture-MS Homo sapiens
10 KSR1  
Affinity Capture-MS Homo sapiens
11 XPO1 7514
Affinity Capture-MS Homo sapiens
12 PIP 5304
Affinity Capture-MS Homo sapiens
13 FBXO10  
Affinity Capture-MS Homo sapiens
14 YWHAE 7531
Affinity Capture-MS Homo sapiens
15 HAUS2  
Affinity Capture-MS Homo sapiens
16 INPP5E 56623
Affinity Capture-MS Homo sapiens
17 S100A2 6273
Affinity Capture-MS Homo sapiens
18 MTCH2 23788
Proximity Label-MS Homo sapiens
19 PRG2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 CCT8L2  
Affinity Capture-MS Homo sapiens
21 SKP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 YWHAZ 7534
Affinity Capture-MS Homo sapiens
23 CNOT2  
Two-hybrid Homo sapiens
24 KIF13B 23303
Affinity Capture-MS Homo sapiens
25 CBY1  
Affinity Capture-MS Homo sapiens
26 OLFM4 10562
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 GHITM 27069
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 OCIAD1 54940
Proximity Label-MS Homo sapiens
29 C6orf141  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 GOLGA6L2  
Affinity Capture-MS Homo sapiens
31 FIS1 51024
Proximity Label-MS Homo sapiens
32 CGN  
Affinity Capture-MS Homo sapiens
33 LRIG1 26018
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 PFDN2 5202
Affinity Capture-MS Homo sapiens
35 ZBTB21  
Affinity Capture-MS Homo sapiens
36 GIGYF1  
Affinity Capture-MS Homo sapiens
37 C1orf109  
Two-hybrid Homo sapiens
38 ANKRD11 29123
Two-hybrid Homo sapiens
39 ARMC1 55156
Two-hybrid Homo sapiens
40 TCEB2 6923
Affinity Capture-MS Homo sapiens
41 CLEC2B  
Affinity Capture-MS Homo sapiens
42 MRPL12 6182
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 PFDN4 5203
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 CCDC96  
Affinity Capture-MS Homo sapiens
45 MAGEA12  
Two-hybrid Homo sapiens
46 PDE3A  
Affinity Capture-MS Homo sapiens
47 SDF4 51150
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 KCTD3  
Affinity Capture-MS Homo sapiens
49 RHOT2 89941
Proximity Label-MS Homo sapiens
50 AKAP1 8165
Proximity Label-MS Homo sapiens
51 RMDN3 55177
Proximity Label-MS Homo sapiens
52 SLC25A46 91137
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which MTFR1L is involved
No pathways found





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