Gene description for KIF13B
Gene name kinesin family member 13B
Gene symbol KIF13B
Other names/aliases GAKIN
Species Homo sapiens
 Database cross references - KIF13B
ExoCarta ExoCarta_23303
Entrez Gene 23303
HGNC 14405
MIM 607350
UniProt Q9NQT8  
 KIF13B identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Thymus 23844026    
 Gene ontology annotations for KIF13B
Molecular Function
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    protein kinase binding GO:0019901 IPI
    microtubule binding GO:0008017 IEA
    ATPase activity GO:0016887 IBA
    microtubule motor activity GO:0003777 NAS
    14-3-3 protein binding GO:0071889 IDA
Biological Process
    metabolic process GO:0008152 NAS
    microtubule-based movement GO:0007018 TAS
    T cell activation GO:0042110 NAS
    regulation of axonogenesis GO:0050770 IDA
    signal transduction GO:0007165 NAS
    protein targeting GO:0006605 TAS
Subcellular Localization
    microtubule GO:0005874 IEA
    cytoplasm GO:0005737 IDA
    axon GO:0030424 IDA
    kinesin complex GO:0005871 IBA
 Experiment description of studies that identified KIF13B in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for KIF13B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DLG1 1739
Invivo Homo sapiens
Invitro Homo sapiens
2 DLG4  
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which KIF13B is involved
No pathways found





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