Gene description for PLEKHA7
Gene name pleckstrin homology domain containing, family A member 7
Gene symbol PLEKHA7
Other names/aliases -
Species Homo sapiens
 Database cross references - PLEKHA7
ExoCarta ExoCarta_144100
Entrez Gene 144100
HGNC 27049
MIM 612686
UniProt Q6IQ23  
 PLEKHA7 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for PLEKHA7
Molecular Function
    delta-catenin binding GO:0070097 IDA
Biological Process
    zonula adherens maintenance GO:0045218 IMP
    epithelial cell-cell adhesion GO:0090136 IMP
Subcellular Localization
    cytoplasm GO:0005737 IDA
    zonula adherens GO:0005915 IDA
    cell junction GO:0030054 IDA
    centrosome GO:0005813 IDA
    extracellular exosome GO:0070062 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified PLEKHA7 in exosomes
1
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for PLEKHA7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PLEKHA7 is involved
No pathways found





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