Gene description for MARK2
Gene name MAP/microtubule affinity-regulating kinase 2
Gene symbol MARK2
Other names/aliases EMK-1
EMK1
PAR-1
Par-1b
Par1b
Species Homo sapiens
 Database cross references - MARK2
ExoCarta ExoCarta_2011
Vesiclepedia VP_2011
Entrez Gene 2011
HGNC 3332
MIM 600526
UniProt Q7KZI7  
 MARK2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
 Gene ontology annotations for MARK2
Molecular Function
    magnesium ion binding GO:0000287 IDA
    RNA binding GO:0003723 HDA
    protein serine/threonine kinase activity GO:0004674 IBA
    protein serine/threonine kinase activity GO:0004674 IDA
    protein serine/threonine kinase activity GO:0004674 ISS
    protein serine/threonine kinase activity GO:0004674 NAS
    protein serine/threonine kinase activity GO:0004674 TAS
    3-phosphoinositide-dependent protein kinase activity GO:0004676 IEA
    DNA-dependent protein kinase activity GO:0004677 IEA
    AMP-activated protein kinase activity GO:0004679 IEA
    eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 IEA
    ribosomal protein S6 kinase activity GO:0004711 IEA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IDA
    lipid binding GO:0008289 IEA
    protein kinase activator activity GO:0030295 TAS
    histone H3S10 kinase activity GO:0035175 IEA
    histone H3T11 kinase activity GO:0035402 IEA
    histone H3T6 kinase activity GO:0035403 IEA
    histone H2AXS139 kinase activity GO:0035979 IEA
    histone H3S28 kinase activity GO:0044022 IEA
    histone H4S1 kinase activity GO:0044023 IEA
    histone H2AS1 kinase activity GO:0044024 IEA
    histone H2BS14 kinase activity GO:0044025 IEA
    cadherin binding GO:0045296 HDA
    tau protein binding GO:0048156 ISS
    tau protein binding GO:0048156 NAS
    tau-protein kinase activity GO:0050321 IBA
    tau-protein kinase activity GO:0050321 IMP
    tau-protein kinase activity GO:0050321 ISS
    tau-protein kinase activity GO:0050321 NAS
    histone H3T3 kinase activity GO:0072354 IEA
    histone H2AS121 kinase activity GO:0072371 IEA
    Rho-dependent protein serine/threonine kinase activity GO:0072518 IEA
    protein serine kinase activity GO:0106310 IEA
    histone H2BS36 kinase activity GO:0140823 IEA
    histone H3S57 kinase activity GO:0140855 IEA
    histone H3T45 kinase activity GO:0140857 IEA
    histone H2AT120 kinase activity GO:1990244 IEA
Biological Process
    microtubule cytoskeleton organization GO:0000226 IBA
    autophagy of mitochondrion GO:0000422 NAS
    neuron migration GO:0001764 ISS
    chromatin remodeling GO:0006338 IEA
    protein phosphorylation GO:0006468 IDA
    protein phosphorylation GO:0006468 IMP
    protein phosphorylation GO:0006468 NAS
    positive regulation of neuron projection development GO:0010976 IDA
    Wnt signaling pathway GO:0016055 IEA
    peptidyl-serine phosphorylation GO:0018105 IDA
    peptidyl-serine phosphorylation GO:0018105 ISS
    establishment of cell polarity GO:0030010 IDA
    establishment of cell polarity GO:0030010 TAS
    intracellular signal transduction GO:0035556 IBA
    intracellular signal transduction GO:0035556 IDA
    establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 IDA
    protein autophosphorylation GO:0046777 ISS
    regulation of axonogenesis GO:0050770 IMP
    regulation of cytoskeleton organization GO:0051493 ISS
    mitochondrion localization GO:0051646 NAS
    axon development GO:0061564 ISS
    regulation of microtubule cytoskeleton organization GO:0070507 IDA
    establishment or maintenance of cell polarity regulating cell shape GO:0071963 ISS
    regulation of microtubule binding GO:1904526 ISS
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    mitochondrion GO:0005739 NAS
    actin filament GO:0005884 IDA
    plasma membrane GO:0005886 IDA
    membrane GO:0016020 IMP
    lateral plasma membrane GO:0016328 IDA
    dendrite GO:0030425 IDA
    microtubule bundle GO:0097427 IDA
 Experiment description of studies that identified MARK2 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
6
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MARK2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 TRAPPC2 6399
Affinity Capture-MS Homo sapiens
3 NUPL2 11097
Affinity Capture-MS Homo sapiens
4 MIS12  
Affinity Capture-MS Homo sapiens
5 ACTR2 10097
Affinity Capture-MS Homo sapiens
6 UTP18  
Affinity Capture-MS Homo sapiens
7 PRKAA1 5562
Affinity Capture-MS Homo sapiens
8 PARD3B 117583
Two-hybrid Homo sapiens
9 HDAC4  
Affinity Capture-MS Homo sapiens
10 UTRN 7402
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
11 ARHGEF2 9181
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
12 PPP2R4 5524
Affinity Capture-Western Homo sapiens
13 OCLN 100506658
Proximity Label-MS Homo sapiens
14 MARCKS 4082
Proximity Label-MS Homo sapiens
15 LAMP3  
Proximity Label-MS Homo sapiens
16 ATG9A 79065
Proximity Label-MS Homo sapiens
17 GJA1 2697
Proximity Label-MS Homo sapiens
18 CASK 8573
Two-hybrid Homo sapiens
19 JAKMIP1 152789
Affinity Capture-MS Homo sapiens
20 RPA2 6118
Two-hybrid Homo sapiens
21 APC  
Affinity Capture-MS Homo sapiens
22 DTNA  
Affinity Capture-MS Homo sapiens
23 GJD3  
Proximity Label-MS Homo sapiens
24 HSP90AB1 3326
Co-fractionation Homo sapiens
25 Soga1  
Affinity Capture-MS Mus musculus
26 DLG5 9231
Affinity Capture-MS Homo sapiens
27 CBY1  
Affinity Capture-MS Homo sapiens
28 PRPF40A 55660
Affinity Capture-MS Homo sapiens
29 STX4 6810
Proximity Label-MS Homo sapiens
30 ARL8B 55207
Affinity Capture-MS Homo sapiens
31 SOX2  
Affinity Capture-MS Homo sapiens
32 GSK3A 2931
Affinity Capture-MS Homo sapiens
33 APEX1 328
Affinity Capture-RNA Homo sapiens
34 KIF13B 23303
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
35 CAPZB 832
Affinity Capture-MS Homo sapiens
36 MARK2 2011
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
37 MLLT4 4301
Proximity Label-MS Homo sapiens
38 PRDX3 10935
Affinity Capture-MS Homo sapiens
39 PMPCA 23203
Affinity Capture-MS Homo sapiens
40 SOGA1 140710
Affinity Capture-MS Homo sapiens
41 KIF5B 3799
Affinity Capture-MS Homo sapiens
42 COL4A3BP 10087
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 YWHAG 7532
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
44 GAB2 9846
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
45 RHOA 387
Affinity Capture-Western Homo sapiens
46 Cenpe  
Affinity Capture-MS Mus musculus
47 PRKCI 5584
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
48 MACC1 346389
Affinity Capture-MS Homo sapiens
49 HERC2 8924
Affinity Capture-MS Homo sapiens
50 STX6 10228
Proximity Label-MS Homo sapiens
51 PPP2R1A 5518
Affinity Capture-MS Homo sapiens
52 SIX2  
Affinity Capture-MS Homo sapiens
53 YWHAH 7533
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
54 ATG16L1 55054
Affinity Capture-MS Homo sapiens
55 CEP57  
Affinity Capture-MS Homo sapiens
56 SFN 2810
Affinity Capture-MS Homo sapiens
57 EIF2A 83939
Biochemical Activity Homo sapiens
58 MARK4  
Affinity Capture-MS Homo sapiens
59 RAB35 11021
Proximity Label-MS Homo sapiens
60 MYCN  
Affinity Capture-MS Homo sapiens
61 TRAPPC11 60684
Affinity Capture-MS Homo sapiens
62 EBAG9 9166
Proximity Label-MS Homo sapiens
63 NEDD4 4734
Biochemical Activity Homo sapiens
64 LAMTOR1 55004
Proximity Label-MS Homo sapiens
65 CCDC9  
Affinity Capture-MS Homo sapiens
66 CLASP2 23122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 DMD 1756
Affinity Capture-Western Homo sapiens
68 KCNE3  
Affinity Capture-MS Homo sapiens
69 YWHAB 7529
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
70 CAV3 859
Affinity Capture-MS Homo sapiens
71 APOO 79135
Proximity Label-MS Homo sapiens
72 MAP3K3 4215
Affinity Capture-MS Homo sapiens
73 GPRASP1  
Affinity Capture-MS Homo sapiens
74 MANSC1 54682
Affinity Capture-MS Homo sapiens
75 RNF41  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
76 CAPZA1 829
Affinity Capture-MS Homo sapiens
77 GSPT1 2935
Affinity Capture-MS Homo sapiens
78 USP21  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
79 CDKN1A  
Affinity Capture-MS Homo sapiens
80 CXADR 1525
Proximity Label-MS Homo sapiens
81 LDHD  
Affinity Capture-MS Homo sapiens
82 LYN 4067
Proximity Label-MS Homo sapiens
83 MCAM 4162
Proximity Label-MS Homo sapiens
84 DNAJC5 80331
Proximity Label-MS Homo sapiens
85 AKR7L 246181
Affinity Capture-MS Homo sapiens
86 HDAC7  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
87 MAPT  
Biochemical Activity Homo sapiens
Co-crystal Structure Homo sapiens
Co-localization Homo sapiens
88 CDH1 999
Proximity Label-MS Homo sapiens
89 YWHAE 7531
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
90 DIRAS3  
Proximity Label-MS Homo sapiens
91 VCP 7415
Affinity Capture-MS Homo sapiens
92 NTRK1 4914
Affinity Capture-MS Homo sapiens
93 IFI16 3428
Affinity Capture-MS Homo sapiens
94 DTX2 113878
Proximity Label-MS Homo sapiens
95 GPSM3  
Affinity Capture-MS Homo sapiens
96 DCTN1 1639
Proximity Label-MS Homo sapiens
97 HUWE1 10075
Affinity Capture-MS Homo sapiens
98 YWHAQ 10971
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Affinity Capture-MS Homo sapiens
99 CEP85L  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 FGF13  
Affinity Capture-MS Homo sapiens
101 PRKCE 5581
Biochemical Activity Homo sapiens
102 RMDN3 55177
Proximity Label-MS Homo sapiens
103 CAMK1 8536
Two-hybrid Homo sapiens
Protein-peptide Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
104 DNAJC5B  
Proximity Label-MS Homo sapiens
105 PARD3 56288
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
106 WDR46  
Affinity Capture-MS Homo sapiens
107 MARK1 4139
Affinity Capture-MS Homo sapiens
108 PHLPP1  
Affinity Capture-MS Homo sapiens
109 FBXL16  
Affinity Capture-MS Homo sapiens
110 NUAK2  
Affinity Capture-MS Homo sapiens
111 PPP2R2B 5521
Affinity Capture-MS Homo sapiens
112 Crtc2  
Biochemical Activity Mus musculus
113 RAB5A 5868
Proximity Label-MS Homo sapiens
114 PANX1 24145
Proximity Label-MS Homo sapiens
115 RC3H2  
Affinity Capture-MS Homo sapiens
116 CCDC82  
Affinity Capture-MS Homo sapiens
117 EPB41L4A 64097
Proximity Label-MS Homo sapiens
118 LAMP1 3916
Proximity Label-MS Homo sapiens
119 YWHAZ 7534
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 Dlg5  
Affinity Capture-MS Mus musculus
121 LAMP2 3920
Proximity Label-MS Homo sapiens
122 FUCA1 2517
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 ARF6 382
Proximity Label-MS Homo sapiens
124 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
125 PKD1 5310
Biochemical Activity Homo sapiens
126 ARL8A 127829
Affinity Capture-MS Homo sapiens
127 TMEM74  
Affinity Capture-MS Homo sapiens
128 GAB1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
129 AP2M1 1173
Affinity Capture-MS Homo sapiens
130 AURKB 9212
Affinity Capture-MS Homo sapiens
131 MAPRE3  
Proximity Label-MS Homo sapiens
132 PRKACA 5566
Proximity Label-MS Homo sapiens
133 CAMSAP2  
Affinity Capture-MS Homo sapiens
134 TADA2A  
Affinity Capture-MS Homo sapiens
135 MYC  
Affinity Capture-MS Homo sapiens
136 RAB9A 9367
Proximity Label-MS Homo sapiens
137 RAB11FIP2  
Biochemical Activity Homo sapiens
138 CDH19  
Affinity Capture-MS Homo sapiens
139 HSPA4 3308
Co-fractionation Homo sapiens
140 CAPZA2 830
Affinity Capture-MS Homo sapiens
141 DDRGK1 65992
Affinity Capture-MS Homo sapiens
142 RHOB 388
Proximity Label-MS Homo sapiens
143 AKT1 207
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
144 BAIAP2 10458
Biochemical Activity Homo sapiens
145 NEDD4L 23327
Biochemical Activity Homo sapiens
146 CCDC8  
Affinity Capture-MS Homo sapiens
147 HECTD1 25831
Affinity Capture-MS Homo sapiens
148 MARK3 4140
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
149 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
150 PHB2 11331
Affinity Capture-MS Homo sapiens
151 NRROS  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
152 PPP2R5E 5529
Affinity Capture-MS Homo sapiens
153 RSF1  
Affinity Capture-MS Homo sapiens
154 PARP1 142
Proximity Label-MS Homo sapiens
155 C11orf58  
Affinity Capture-MS Homo sapiens
156 PTPRD 5789
Reconstituted Complex Homo sapiens
157 RBM25 58517
Affinity Capture-MS Homo sapiens
158 PARD6G 84552
Affinity Capture-MS Homo sapiens
159 FRYL 285527
Affinity Capture-MS Homo sapiens
160 USP36  
Affinity Capture-MS Homo sapiens
161 EZR 7430
Proximity Label-MS Homo sapiens
162 LCK 3932
Proximity Label-MS Homo sapiens
163 SMURF1 57154
Biochemical Activity Homo sapiens
164 CDK15  
Affinity Capture-MS Homo sapiens
165 HSP90AA1 3320
Co-fractionation Homo sapiens
166 KIFAP3 22920
Two-hybrid Homo sapiens
167 C11orf52 91894
Proximity Label-MS Homo sapiens
168 MKI67  
Affinity Capture-MS Homo sapiens
169 LMAN1 3998
Proximity Label-MS Homo sapiens
170 UFL1 23376
Affinity Capture-MS Homo sapiens
171 NF1 4763
Negative Genetic Homo sapiens
172 CLASP1 23332
Affinity Capture-MS Homo sapiens
173 RAB2A 5862
Proximity Label-MS Homo sapiens
174 B3GAT1  
Proximity Label-MS Homo sapiens
175 C16orf72 29035
Affinity Capture-MS Homo sapiens
176 PDCD7  
Affinity Capture-MS Homo sapiens
177 PINK1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
178 RAB11A 8766
Proximity Label-MS Homo sapiens
179 FLOT1 10211
Proximity Label-MS Homo sapiens
180 STK11 6794
Biochemical Activity Homo sapiens
181 EPHA2 1969
Proximity Label-MS Homo sapiens
182 KRAS 3845
Synthetic Lethality Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
183 RAB5C 5878
Proximity Label-MS Homo sapiens
184 TMCC2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
185 MTCL1 23255
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
186 RC3H1 149041
Affinity Capture-MS Homo sapiens
187 SNTB2 6645
Affinity Capture-MS Homo sapiens
188 PARD6A  
Affinity Capture-Western Homo sapiens
189 CAV1 857
Proximity Label-MS Homo sapiens
190 NAP1L5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
191 CDC5L 988
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which MARK2 is involved
No pathways found





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