Gene description for COL4A3BP
Gene name collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
Gene symbol COL4A3BP
Other names/aliases CERT
CERTL
GPBP
MRD34
STARD11
Species Homo sapiens
 Database cross references - COL4A3BP
ExoCarta ExoCarta_10087
Vesiclepedia VP_10087
Entrez Gene 10087
HGNC 2205
MIM 604677
UniProt Q9Y5P4  
 COL4A3BP identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for COL4A3BP
Molecular Function
    protein binding GO:0005515 IPI
    protein kinase activity GO:0004672 TAS
    ceramide binding GO:0097001 IDA
    phosphatidylinositol-4-phosphate binding GO:0070273 IDA
    ceramide transporter activity GO:0035620 IDA
Biological Process
    sphingolipid biosynthetic process GO:0030148 TAS
    small molecule metabolic process GO:0044281 TAS
    signal transduction GO:0007165 IEA
    ceramide metabolic process GO:0006672 IEA
    lipid homeostasis GO:0055088 IEA
    sphingolipid metabolic process GO:0006665 TAS
    ER to Golgi ceramide transport GO:0035621 IMP
    muscle contraction GO:0006936 IEA
    cell morphogenesis GO:0000902 IEA
    endoplasmic reticulum organization GO:0007029 IEA
    mitochondrion morphogenesis GO:0070584 IEA
    response to endoplasmic reticulum stress GO:0034976 IEA
    immune response GO:0006955 NAS
    heart morphogenesis GO:0003007 IEA
    cell proliferation GO:0008283 IEA
    in utero embryonic development GO:0001701 IEA
    protein phosphorylation GO:0006468 TAS
Subcellular Localization
    mitochondrion GO:0005739 IEA
    endoplasmic reticulum membrane GO:0005789 TAS
    nucleoplasm GO:0005654 IDA
    perinuclear region of cytoplasm GO:0048471 IDA
    cytosol GO:0005829 TAS
    Golgi apparatus GO:0005794 IDA
 Experiment description of studies that identified COL4A3BP in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for COL4A3BP
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CSNK1G2 1455
Two-hybrid Homo sapiens
2 ITGB3BP  
Two-hybrid Homo sapiens
3 POM121  
Two-hybrid Homo sapiens
4 COL4A3BP 10087
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
5 RTN3 10313
Two-hybrid Homo sapiens
6 RTN4 57142
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which COL4A3BP is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here