Gene description for TAF15
Gene name
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
Gene symbol
TAF15
Other names/aliases
Npl3 RBP56 TAF2N TAFII68
Species
Homo sapiens
Database cross references - TAF15
ExoCarta
ExoCarta_8148
Entrez Gene
8148
HGNC
11547
MIM
601574
UniProt
Q92804
TAF15 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells
26054723
Hepatocellular carcinoma cells
26054723
Gene ontology annotations for TAF15
Experiment description of studies that identified TAF15 in exosomes
1
Experiment ID
235
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
2
Experiment ID
236
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
MHCC97L
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
Protein-protein interactions for TAF15
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
TAF5
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
2
POLR2C
5432
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
3
TBP
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
4
POLR2E
5434
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
5
TAF7
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
6
TAF11
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
7
SF1
7536
Reconstituted Complex
Homo sapiens
8
PRMT1
3276
Biochemical Activity
Homo sapiens
9
SAFB
Reconstituted Complex
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
10
TAF13
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
11
POLR2G
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
View the network
image/svg+xml
Pathways in which TAF15 is involved
No pathways found