Gene description for SNRPC
Gene name small nuclear ribonucleoprotein polypeptide C
Gene symbol SNRPC
Other names/aliases U1C
Yhc1
Species Homo sapiens
 Database cross references - SNRPC
ExoCarta ExoCarta_6631
Vesiclepedia VP_6631
Entrez Gene 6631
HGNC 11157
MIM 603522
UniProt P09234  
 SNRPC identified in exosomes derived from the following tissue/cell type
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
 Gene ontology annotations for SNRPC
Molecular Function
    protein binding GO:0005515 IPI
    U1 snRNA binding GO:0030619 IDA
    zinc ion binding GO:0008270 IDA
    protein homodimerization activity GO:0042803 IPI
    single-stranded RNA binding GO:0003727 IDA
    mRNA binding GO:0003729 IEA
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    spliceosomal snRNP assembly GO:0000387 IDA
    mRNA 5'-splice site recognition GO:0000395 IEA
    mRNA splicing, via spliceosome GO:0000398 IDA
Subcellular Localization
    U2-type prespliceosome GO:0071004 IEA
    U1 snRNP GO:0005685 IDA
    Cajal body GO:0015030 IDA
    commitment complex GO:0000243 IEA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified SNRPC in exosomes
1
Experiment ID 363
MISEV standards
EV Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
EV Enriched markers
DCLK1
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M.
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 364
MISEV standards
EV Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
EV Enriched markers
DCLK1
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M.
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
3
Experiment ID 365
MISEV standards
EV Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
EV Enriched markers
DCLK1
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M.
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for SNRPC
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SNRNP70 6625
Invivo Homo sapiens
Invitro Homo sapiens
2 EWSR1 2130
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which SNRPC is involved
No pathways found





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