Gene description for RERE
Gene name arginine-glutamic acid dipeptide (RE) repeats
Gene symbol RERE
Other names/aliases ARG
ARP
ATN1L
DNB1
Species Homo sapiens
 Database cross references - RERE
ExoCarta ExoCarta_473
Entrez Gene 473
HGNC 9965
MIM 605226
UniProt Q9P2R6  
 RERE identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for RERE
Molecular Function
    sequence-specific DNA binding GO:0043565 IEA
    zinc ion binding GO:0008270 IEA
    sequence-specific DNA binding transcription factor activity GO:0003700 IEA
    protein binding GO:0005515 IPI
    poly-glutamine tract binding GO:0008267 TAS
    chromatin binding GO:0003682 IEA
Biological Process
    chromatin remodeling GO:0006338 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
    transcription, DNA-templated GO:0006351 IEA
    multicellular organismal development GO:0007275 IEA
    NLS-bearing protein import into nucleus GO:0006607 TAS
Subcellular Localization
    nucleus GO:0005634 NAS
    histone deacetylase complex GO:0000118 IEA
 Experiment description of studies that identified RERE in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for RERE
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ATN1  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
2 TRIP6 7205
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which RERE is involved
No pathways found





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