Gene description for LZTR1
Gene name leucine-zipper-like transcription regulator 1
Gene symbol LZTR1
Other names/aliases BTBD29
LZTR-1
SWNTS2
Species Homo sapiens
 Database cross references - LZTR1
ExoCarta ExoCarta_8216
Entrez Gene 8216
HGNC 6742
MIM 600574
UniProt Q8N653  
 LZTR1 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for LZTR1
Molecular Function
    sequence-specific DNA binding transcription factor activity GO:0003700 TAS
Biological Process
    regulation of transcription, DNA-templated GO:0006355 TAS
    anatomical structure morphogenesis GO:0009653 TAS
 Experiment description of studies that identified LZTR1 in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for LZTR1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LZTR1 is involved
No pathways found





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