Gene description for ALG13
Gene name ALG13, UDP-N-acetylglucosaminyltransferase subunit
Gene symbol ALG13
Other names/aliases CDG1S
CXorf45
GLT28D1
MDS031
TDRD13
YGL047W
Species Homo sapiens
 Database cross references - ALG13
ExoCarta ExoCarta_79868
Entrez Gene 79868
HGNC 30881
MIM 300776
UniProt Q9NP73  
 ALG13 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for ALG13
Molecular Function
    cysteine-type peptidase activity GO:0008234 IEA
    poly(A) RNA binding GO:0044822 IDA
    protein binding GO:0005515 IPI
    N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity GO:0004577 IEA
    carbohydrate binding GO:0030246 IEA
Biological Process
    protein N-linked glycosylation via asparagine GO:0018279 TAS
    lipid glycosylation GO:0030259 IEA
    dolichol-linked oligosaccharide biosynthetic process GO:0006488 TAS
    cellular protein metabolic process GO:0044267 TAS
    post-translational protein modification GO:0043687 TAS
    proteolysis GO:0006508 IEA
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 TAS
 Experiment description of studies that identified ALG13 in exosomes
1
Experiment ID 235
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for ALG13
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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