Gene description for NDUFA7
Gene name NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
Gene symbol NDUFA7
Other names/aliases B14.5a
Species Homo sapiens
 Database cross references - NDUFA7
ExoCarta ExoCarta_4701
Vesiclepedia VP_4701
Entrez Gene 4701
HGNC 7691
MIM 602139
UniProt O95182  
 NDUFA7 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for NDUFA7
Molecular Function
    protein binding GO:0005515 IPI
    NADH dehydrogenase (ubiquinone) activity GO:0008137 NAS
Biological Process
    mitochondrial electron transport, NADH to ubiquinone GO:0006120 IBA
    mitochondrial electron transport, NADH to ubiquinone GO:0006120 NAS
    aerobic respiration GO:0009060 NAS
    proton motive force-driven mitochondrial ATP synthesis GO:0042776 NAS
    proton transmembrane transport GO:1902600 IEA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial inner membrane GO:0005743 TAS
    respiratory chain complex I GO:0045271 IBA
    respiratory chain complex I GO:0045271 IDA
    respiratory chain complex I GO:0045271 NAS
 Experiment description of studies that identified NDUFA7 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for NDUFA7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SLIRP 81892
Proximity Label-MS Homo sapiens
2 Tmed2 56334
Affinity Capture-MS Mus musculus
3 PQBP1  
Co-fractionation Homo sapiens
4 NDUFB8 4714
Affinity Capture-MS Homo sapiens
5 SNX3 8724
Co-fractionation Homo sapiens
6 UBE4B 10277
Co-fractionation Homo sapiens
7 UBL4A 8266
Co-fractionation Homo sapiens
8 RAB8A 4218
Co-fractionation Homo sapiens
9 VAPA 9218
Affinity Capture-MS Homo sapiens
10 GJA1 2697
Affinity Capture-MS Homo sapiens
11 ACAA1 30
Co-fractionation Homo sapiens
12 TRUB2  
Proximity Label-MS Homo sapiens
13 MTG2  
Proximity Label-MS Homo sapiens
14 NGRN  
Proximity Label-MS Homo sapiens
15 CHCHD1  
Proximity Label-MS Homo sapiens
16 NABP2  
Co-fractionation Homo sapiens
17 NDUFS7 374291
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 NDUFA4 4697
Affinity Capture-MS Homo sapiens
19 DNAJC15  
Proximity Label-MS Homo sapiens
20 MTRF1  
Proximity Label-MS Homo sapiens
21 GFM2 84340
Proximity Label-MS Homo sapiens
22 CCDC90B  
Proximity Label-MS Homo sapiens
23 SLC25A24 29957
Co-fractionation Homo sapiens
24 LRPPRC 10128
Proximity Label-MS Homo sapiens
25 FOXA1  
Affinity Capture-MS Homo sapiens
26 NDUFB9 4715
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
27 OLA1 29789
Co-fractionation Homo sapiens
28 NDUFS3 4722
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 TFAM 7019
Proximity Label-MS Homo sapiens
30 PMPCA 23203
Proximity Label-MS Homo sapiens
31 C8orf82  
Proximity Label-MS Homo sapiens
32 HINT2 84681
Proximity Label-MS Homo sapiens
33 NDUFA5 4698
Cross-Linking-MS (XL-MS) Homo sapiens
34 STX7 8417
Co-fractionation Homo sapiens
35 SRRM2 23524
Co-fractionation Homo sapiens
36 PIN4 5303
Co-fractionation Homo sapiens
37 C1qbp 12261
Affinity Capture-MS Mus musculus
38 MRPS26 64949
Proximity Label-MS Homo sapiens
39 SURF1  
Proximity Label-MS Homo sapiens
40 SNRPC 6631
Co-fractionation Homo sapiens
41 EXD2  
Proximity Label-MS Homo sapiens
42 NDUFV1 4723
Affinity Capture-MS Homo sapiens
43 TOMM40 10452
Co-fractionation Homo sapiens
44 NDUFV3 4731
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 ATP5H 10476
Co-fractionation Homo sapiens
46 PMPCB 9512
Proximity Label-MS Homo sapiens
47 TACO1  
Proximity Label-MS Homo sapiens
48 FASTKD2  
Proximity Label-MS Homo sapiens
49 NDUFA6  
Affinity Capture-MS Homo sapiens
50 VWA8 23078
Proximity Label-MS Homo sapiens
51 SSMEM1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 NDUFS5 4725
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 MTERF3  
Proximity Label-MS Homo sapiens
54 MDH2 4191
Proximity Label-MS Homo sapiens
55 ENPP6 133121
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 C6orf203  
Proximity Label-MS Homo sapiens
57 NDUFS4 4724
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 COX15 1355
Proximity Label-MS Homo sapiens
59 FASTKD5  
Proximity Label-MS Homo sapiens
60 NDUFB7 4713
Affinity Capture-MS Homo sapiens
61 TBL2 26608
Co-fractionation Homo sapiens
62 ND2 4536
Affinity Capture-MS Homo sapiens
63 NDUFS8 4728
Affinity Capture-MS Homo sapiens
64 ND5 4540
Affinity Capture-MS Homo sapiens
65 HRSP12 10247
Co-fractionation Homo sapiens
66 NDUFA8 4702
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 UBE2I 7329
Co-fractionation Homo sapiens
68 NDUFAB1 4706
Affinity Capture-MS Homo sapiens
69 TUFM 7284
Proximity Label-MS Homo sapiens
70 HSCB 150274
Proximity Label-MS Homo sapiens
71 PDLIM5 10611
Co-fractionation Homo sapiens
72 CYB5A 1528
Co-fractionation Homo sapiens
73 NDUFB2 4708
Affinity Capture-MS Homo sapiens
74 ND1  
Affinity Capture-MS Homo sapiens
75 CCDC109B 55013
Proximity Label-MS Homo sapiens
76 CDV3 55573
Co-fractionation Homo sapiens
77 MCU 90550
Proximity Label-MS Homo sapiens
78 TMX2 51075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 QKI 9444
Co-fractionation Homo sapiens
80 MRPL11 65003
Proximity Label-MS Homo sapiens
81 MTRF1L  
Proximity Label-MS Homo sapiens
82 DNAJC30  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 PRKAB1 5564
Two-hybrid Homo sapiens
84 TMEM70  
Proximity Label-MS Homo sapiens
85 ARMCX2 9823
Co-fractionation Homo sapiens
86 ATP5B 506
Co-fractionation Homo sapiens
87 SUGP1  
Co-fractionation Homo sapiens
88 CRELD1 78987
Affinity Capture-MS Homo sapiens
89 TPX2  
Co-fractionation Homo sapiens
90 MRPL14 64928
Co-fractionation Homo sapiens
91 Rab5c 19345
Affinity Capture-MS Mus musculus
92 C15orf48  
Affinity Capture-MS Homo sapiens
93 KIAA0101  
Co-fractionation Homo sapiens
94 OTC 5009
Proximity Label-MS Homo sapiens
95 MRRF  
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
96 VAPB 9217
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
97 MRPS12  
Proximity Label-MS Homo sapiens
98 MTIF2 4528
Proximity Label-MS Homo sapiens
99 NDUFB10 4716
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
100 NDUFA13 51079
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
101 NDUFA9 4704
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 RTP2  
Two-hybrid Homo sapiens
103 CLPP 8192
Proximity Label-MS Homo sapiens
104 MTIF3  
Proximity Label-MS Homo sapiens
105 UBE2L3 7332
Co-fractionation Homo sapiens
106 Bmpr1a  
Affinity Capture-MS Mus musculus
107 GOLT1B 51026
Affinity Capture-MS Homo sapiens
108 Rmdn3  
Affinity Capture-MS Mus musculus
109 BCAP31 10134
Co-fractionation Homo sapiens
110 COX6A1  
Co-fractionation Homo sapiens
111 RBMS1 5937
Co-fractionation Homo sapiens
112 COX6B1 1340
Affinity Capture-MS Homo sapiens
113 RBM27  
Co-fractionation Homo sapiens
114 NUP214 8021
Co-fractionation Homo sapiens
115 ZC3H11A  
Co-fractionation Homo sapiens
116 TAGLN 6876
Co-fractionation Homo sapiens
117 C17orf80 55028
Proximity Label-MS Homo sapiens
118 MRPS28  
Co-fractionation Homo sapiens
119 ECI2 10455
Co-fractionation Homo sapiens
120 C12orf65  
Proximity Label-MS Homo sapiens
121 RPUSD4 84881
Proximity Label-MS Homo sapiens
122 NDUFB3 4709
Affinity Capture-MS Homo sapiens
123 NDUFA2 4695
Affinity Capture-MS Homo sapiens
124 CYP2J2  
Affinity Capture-MS Homo sapiens
125 MPLKIP  
Co-fractionation Homo sapiens
126 NDUFB6 4712
Affinity Capture-MS Homo sapiens
127 ACAD9 28976
Proximity Label-MS Homo sapiens
128 NDUFA3  
Affinity Capture-MS Homo sapiens
129 NDUFA10 4705
Affinity Capture-MS Homo sapiens
130 NDUFV2 4729
Affinity Capture-MS Homo sapiens
131 NDUFC2 4718
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 METTL15  
Proximity Label-MS Homo sapiens
133 UPF2 26019
Two-hybrid Homo sapiens
134 NDUFS1 4719
Affinity Capture-MS Homo sapiens
135 MCUR1 63933
Proximity Label-MS Homo sapiens
136 NDUFS2 4720
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
137 FUT1  
Affinity Capture-MS Homo sapiens
138 TTPA  
Two-hybrid Homo sapiens
139 SAYSD1  
Affinity Capture-MS Homo sapiens
140 SBDS 51119
Co-fractionation Homo sapiens
141 NDUFA1 4694
Affinity Capture-MS Homo sapiens
142 CS 1431
Proximity Label-MS Homo sapiens
143 PDLIM7 9260
Co-fractionation Homo sapiens
144 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
145 TSFM 10102
Proximity Label-MS Homo sapiens
146 AUH 549
Proximity Label-MS Homo sapiens
147 RRBP1 6238
Co-fractionation Homo sapiens
148 TBRG4 9238
Proximity Label-MS Homo sapiens
149 DNAJC19 131118
Proximity Label-MS Homo sapiens
150 NDUFAF2  
Affinity Capture-MS Homo sapiens
151 ICT1 3396
Proximity Label-MS Homo sapiens
152 LONP1 9361
Proximity Label-MS Homo sapiens
153 SCP2 6342
Co-fractionation Homo sapiens
154 GATAD2B 57459
Co-fractionation Homo sapiens
155 DNAJA3 9093
Proximity Label-MS Homo sapiens
156 NDUFA12 55967
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 RPS10P5 93144
Co-fractionation Homo sapiens
158 NDUFB1 4707
Affinity Capture-MS Homo sapiens
159 C21orf33  
Proximity Label-MS Homo sapiens
160 SSBP1 6742
Proximity Label-MS Homo sapiens
161 MMGT1 93380
Affinity Capture-MS Homo sapiens
162 FASTKD3  
Proximity Label-MS Homo sapiens
163 RPS28 6234
Co-fractionation Homo sapiens
164 PIN1 5300
Co-fractionation Homo sapiens
165 RPL38 6169
Co-fractionation Homo sapiens
166 GFM1 85476
Proximity Label-MS Homo sapiens
167 RFX5 5993
Co-fractionation Homo sapiens
168 TEFM  
Proximity Label-MS Homo sapiens
169 RAB7A 7879
Affinity Capture-MS Homo sapiens
170 SLC25A51  
Proximity Label-MS Homo sapiens
171 NDUFB5 4711
Affinity Capture-MS Homo sapiens
172 RPUSD3  
Proximity Label-MS Homo sapiens
173 GRSF1 2926
Proximity Label-MS Homo sapiens
174 C1QBP 708
Proximity Label-MS Homo sapiens
175 SERBP1 26135
Affinity Capture-MS Homo sapiens
176 RAB5C 5878
Affinity Capture-MS Homo sapiens
177 NDUFB11 54539
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
178 LMO1  
Two-hybrid Homo sapiens
179 METTL17  
Proximity Label-MS Homo sapiens
180 ND4 4538
Affinity Capture-MS Homo sapiens
181 NDUFS6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
182 RANGAP1 5905
Co-fractionation Homo sapiens
183 DDX28  
Proximity Label-MS Homo sapiens
184 TIMM44 10469
Co-fractionation Homo sapiens
185 VDAC3 7419
Co-fractionation Homo sapiens
186 SCO2  
Co-fractionation Homo sapiens
187 NDUFB4 4710
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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