Gene description for ARMCX2
Gene name armadillo repeat containing, X-linked 2
Gene symbol ARMCX2
Other names/aliases ALEX2
GASP9
Species Homo sapiens
 Database cross references - ARMCX2
ExoCarta ExoCarta_9823
Vesiclepedia VP_9823
Entrez Gene 9823
HGNC 16869
MIM 300363
UniProt Q7L311  
 ARMCX2 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for ARMCX2
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrial outer membrane GO:0005741 IEA
 Experiment description of studies that identified ARMCX2 in sEVs
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ARMCX2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 IMMT 10989
Co-fractionation Homo sapiens
2 OCIAD1 54940
Proximity Label-MS Homo sapiens
3 AKAP1 8165
Proximity Label-MS Homo sapiens
4 PML 5371
Affinity Capture-MS Homo sapiens
5 MAVS 57506
Proximity Label-MS Homo sapiens
6 WFS1 7466
Co-fractionation Homo sapiens
7 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
8 LRRC59 55379
Co-fractionation Homo sapiens
9 NDUFS4 4724
Co-fractionation Homo sapiens
10 FIS1 51024
Proximity Label-MS Homo sapiens
11 RMDN3 55177
Proximity Label-MS Homo sapiens
12 VIM 7431
Two-hybrid Homo sapiens
13 CHCHD3 54927
Co-fractionation Homo sapiens
14 NDUFA2 4695
Co-fractionation Homo sapiens
15 ARMCX2 9823
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
16 NDUFS1 4719
Co-fractionation Homo sapiens
17 RHOT2 89941
Proximity Label-MS Homo sapiens
18 RHOXF2  
Two-hybrid Homo sapiens
19 NDUFA7 4701
Co-fractionation Homo sapiens
20 EXD2  
Proximity Label-MS Homo sapiens
21 KTN1 3895
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which ARMCX2 is involved
No pathways found





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