Gene description for MAVS
Gene name	mitochondrial antiviral signaling protein
Gene symbol	MAVS
Other names/aliases	CARDIF IPS-1 IPS1 VISA
Species	Homo sapiens
Database cross references - MAVS
ExoCarta	ExoCarta_57506
Entrez Gene	57506
HGNC	29233
MIM	609676
UniProt	Q7Z434
MAVS identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for MAVS

Molecular Function     protein kinase binding GO:0019901 IPI     signal transducer activity GO:0004871 IMP     CARD domain binding GO:0050700 IPI     protein binding GO:0005515 IPI Biological Process     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 IMP     positive regulation of interferon-beta production GO:0032728 IMP     positive regulation of protein phosphorylation GO:0001934 IDA     regulation of peroxisome organization GO:1900063 IMP     positive regulation of chemokine (C-C motif) ligand 5 production GO:0071651 IDA     positive regulation of interferon-alpha production GO:0032727 IMP     positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 IDA     innate immune response GO:0045087 TAS     positive regulation of protein import into nucleus, translocation GO:0033160 IDA     positive regulation of transcription factor import into nucleus GO:0042993 IDA     positive regulation of interleukin-8 production GO:0032757 IDA     cellular response to exogenous dsRNA GO:0071360 IMP     positive regulation of defense response to virus by host GO:0002230 IMP     signal transduction GO:0007165 IMP     viral process GO:0016032 IEA     positive regulation of tumor necrosis factor production GO:0032760 IDA     negative regulation of viral genome replication GO:0045071 IDA     defense response to virus GO:0051607 IDA     RIG-I signaling pathway GO:0039529 IEA     activation of innate immune response GO:0002218 IMP     positive regulation of type I interferon-mediated signaling pathway GO:0060340 IDA     positive regulation of IP-10 production GO:0071660 IDA     negative regulation of type I interferon production GO:0032480 TAS     defense response to bacterium GO:0042742 IMP     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA Subcellular Localization     mitochondrion GO:0005739 IDA     mitochondrial membrane GO:0031966 IDA     integral component of membrane GO:0016021 IEA     mitochondrial outer membrane GO:0005741 TAS     peroxisomal membrane GO:0005778 IDA