Experiment description of studies that identified DNAH17 in exosomes

1 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

2 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for DNAH17

Protein Interactor ExoCarta ID Identification method PubMed Species 1 PA2G4 5036 Cross-Linking-MS (XL-MS) Homo sapiens 2 HNRNPH1 3187 Affinity Capture-RNA Homo sapiens 3 TVP23C   Affinity Capture-MS Homo sapiens 4 AMY1C 278 Affinity Capture-MS Homo sapiens 5 SLC16A1 6566 Cross-Linking-MS (XL-MS) Homo sapiens 6 IRS4 8471 Affinity Capture-Luminescence Homo sapiens Affinity Capture-MS Homo sapiens 7 MAVS 57506 Affinity Capture-MS Homo sapiens 8 HSPA5 3309 Cross-Linking-MS (XL-MS) Homo sapiens 9 MUL1   Affinity Capture-MS Homo sapiens 10 CUL3 8452 Affinity Capture-MS Homo sapiens 11 CLN3 1201 Affinity Capture-MS Homo sapiens 12 RBM14-RBM4 100526737 Affinity Capture-MS Homo sapiens 13 IGHA2 3494 Affinity Capture-MS Homo sapiens 14 CAPNS1 826 Cross-Linking-MS (XL-MS) Homo sapiens 15 TP53 7157 Affinity Capture-MS Homo sapiens 16 OMA1   Affinity Capture-MS Homo sapiens 17 ZG16B 124220 Affinity Capture-MS Homo sapiens 18 PKM 5315 Cross-Linking-MS (XL-MS) Homo sapiens 19 HSP90B1 7184 Cross-Linking-MS (XL-MS) Homo sapiens 20 CRNN 49860 Affinity Capture-MS Homo sapiens View the network

Pathways in which DNAH17 is involved

No pathways found