Gene description for PRKACB
Gene name protein kinase, cAMP-dependent, catalytic, beta
Gene symbol PRKACB
Other names/aliases PKA C-beta
PKACB
Species Homo sapiens
 Database cross references - PRKACB
ExoCarta ExoCarta_5567
Vesiclepedia VP_5567
Entrez Gene 5567
HGNC 9381
MIM 176892
UniProt P22694  
 PRKACB identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Thymus 23844026    
 Gene ontology annotations for PRKACB
Molecular Function
    magnesium ion binding GO:0000287 IDA
    protein serine/threonine kinase activity GO:0004674 TAS
    cAMP-dependent protein kinase activity GO:0004691 IBA
    cAMP-dependent protein kinase activity GO:0004691 IDA
    cAMP-dependent protein kinase activity GO:0004691 TAS
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IDA
    ubiquitin protein ligase binding GO:0031625 IDA
    protein serine kinase activity GO:0106310 IEA
Biological Process
    neural tube closure GO:0001843 IEA
    renal water homeostasis GO:0003091 TAS
    protein phosphorylation GO:0006468 IDA
    signal transduction GO:0007165 IBA
    adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO:0007188 TAS
    high-density lipoprotein particle assembly GO:0034380 TAS
    negative regulation of smoothened signaling pathway GO:0045879 IEA
    regulation of protein processing GO:0070613 IEA
    negative regulation of TORC1 signaling GO:1904262 IDA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 TAS
    centrosome GO:0005813 IDA
    cytosol GO:0005829 IBA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IEA
    cAMP-dependent protein kinase complex GO:0005952 IBA
    cAMP-dependent protein kinase complex GO:0005952 TAS
    extracellular exosome GO:0070062 HDA
    ciliary base GO:0097546 TAS
 Experiment description of studies that identified PRKACB in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
7
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PRKACB
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ACTR2 10097
Co-fractionation Homo sapiens
2 AKAP8  
Affinity Capture-MS Homo sapiens
3 KLHL28  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 PER1  
Affinity Capture-MS Homo sapiens
5 VAPA 9218
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 ARPC2 10109
Co-fractionation Homo sapiens
7 GPR161  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 TARDBP 23435
Affinity Capture-MS Homo sapiens
9 ARPC4 10093
Co-fractionation Homo sapiens
10 AKAP11 11215
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 DDX17 10521
Affinity Capture-MS Homo sapiens
12 PRKACG  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 HIST1H2BB 3018
Affinity Capture-MS Homo sapiens
14 ETFB 2109
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 HSP90AB1 3326
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
16 CSNK2A1 1457
Biochemical Activity Homo sapiens
17 RABGGTB 5876
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 PRKDC 5591
Affinity Capture-MS Homo sapiens
19 AKAP8L  
Affinity Capture-MS Homo sapiens
20 H2AFV 94239
Affinity Capture-MS Homo sapiens
21 GSK3A 2931
Affinity Capture-MS Homo sapiens
22 DDX23 9416
Affinity Capture-MS Homo sapiens
23 HP 3240
Affinity Capture-MS Homo sapiens
24 TRIM28 10155
Affinity Capture-MS Homo sapiens
25 SULF2 55959
Affinity Capture-MS Homo sapiens
26 DYRK1A 1859
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 PKIA  
Two-hybrid Homo sapiens
28 ACTR3 10096
Co-fractionation Homo sapiens
29 NAA11 84779
Affinity Capture-MS Homo sapiens
30 GLTSCR2  
Affinity Capture-MS Homo sapiens
31 ARMCX4  
Affinity Capture-MS Homo sapiens
32 HIST2H3A 333932
Cross-Linking-MS (XL-MS) Homo sapiens
33 RECQL4  
Affinity Capture-MS Homo sapiens
34 TNP2  
Biochemical Activity Homo sapiens
35 TFIP11  
Affinity Capture-MS Homo sapiens
36 HIST4H4 121504
Affinity Capture-MS Homo sapiens
37 Gsk3b  
Affinity Capture-MS Mus musculus
38 DYNLL1 8655
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 HIST1H2AA 221613
Affinity Capture-MS Homo sapiens
40 CEP57  
Affinity Capture-MS Homo sapiens
41 MAVS 57506
Affinity Capture-Western Homo sapiens
42 NPAS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 MAP2 4133
Affinity Capture-MS Homo sapiens
44 XPO1 7514
Affinity Capture-MS Homo sapiens
45 PPP1CA 5499
Affinity Capture-MS Homo sapiens
46 HSP90AB4P 664618
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 CDKN2AIP  
Affinity Capture-MS Homo sapiens
48 FKBP5 2289
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 NHEJ1  
Affinity Capture-Western Homo sapiens
50 PARK2  
Affinity Capture-MS Homo sapiens
51 HSP90B1 7184
Cross-Linking-MS (XL-MS) Homo sapiens
52 NONO 4841
Affinity Capture-MS Homo sapiens
53 MAPRE1 22919
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 RPE  
Co-fractionation Homo sapiens
55 HIST1H3J 8356
Affinity Capture-MS Homo sapiens
56 ACVR1B 91
Two-hybrid Homo sapiens
57 FGG 2266
Affinity Capture-MS Homo sapiens
58 NGFR 4804
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
59 DDX5 1655
Affinity Capture-MS Homo sapiens
60 NTRK1 4914
Affinity Capture-MS Homo sapiens
61 DCAF7 10238
Affinity Capture-MS Homo sapiens
62 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
63 RPL27A 6157
Two-hybrid Homo sapiens
64 NAPG 8774
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 TPRKB 51002
Co-fractionation Homo sapiens
66 DHX9 1660
Affinity Capture-MS Homo sapiens
67 DYNLL2 140735
Affinity Capture-MS Homo sapiens
68 PRKAR1B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 Cdk5rap2  
Affinity Capture-MS Mus musculus
70 FGFR1OP  
Affinity Capture-MS Homo sapiens
71 ARFGAP1 55738
Two-hybrid Homo sapiens
72 RAN 5901
Affinity Capture-MS Homo sapiens
73 POLR2B 5431
Affinity Capture-MS Homo sapiens
74 FGD5  
Affinity Capture-MS Homo sapiens
75 PICK1  
Affinity Capture-MS Homo sapiens
76 POLR2C 5432
Affinity Capture-MS Homo sapiens
77 VAPB 9217
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 FGF14  
Affinity Capture-MS Homo sapiens
79 ARPC1B 10095
Co-fractionation Homo sapiens
80 AKAP14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 MAD1L1  
Affinity Capture-MS Homo sapiens
82 AKAP9 10142
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 PRKAR2A 5576
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 C11orf49  
Affinity Capture-MS Homo sapiens
85 PRKAR1A 5573
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 RAD51B  
Affinity Capture-MS Homo sapiens
87 TRAF6 7189
Affinity Capture-Western Homo sapiens
88 DCLRE1C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 FUS 2521
Affinity Capture-MS Homo sapiens
90 H3F3B 3021
Affinity Capture-MS Homo sapiens
91 DUSP16  
Affinity Capture-MS Homo sapiens
92 TRAF3 7187
Affinity Capture-Western Homo sapiens
93 TNP1  
Biochemical Activity Homo sapiens
94 AP2M1 1173
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 CDK5RAP2 55755
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 MLF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
97 KCNE3  
Affinity Capture-MS Homo sapiens
98 HSP90AA4P 3323
Affinity Capture-MS Homo sapiens
99 CCNL2 81669
Affinity Capture-MS Homo sapiens
100 KIF1BP 26128
Co-fractionation Homo sapiens
101 Uso1 56041
Affinity Capture-MS Mus musculus
102 NIN 51199
Proximity Label-MS Homo sapiens
103 HIST1H2BA 255626
Affinity Capture-MS Homo sapiens
104 AKAP5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 CREB3L3  
Affinity Capture-MS Homo sapiens
106 TOP1 7150
Affinity Capture-MS Homo sapiens
107 TP53RK 112858
Co-fractionation Homo sapiens
108 CORO1A 11151
Affinity Capture-MS Homo sapiens
109 MATR3 9782
Affinity Capture-MS Homo sapiens
110 AKAP7 9465
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
111 BMP1 649
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 LMNA 4000
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 Prkar2a 19087
Affinity Capture-MS Mus musculus
114 AKAP1 8165
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 XRCC5 7520
Affinity Capture-MS Homo sapiens
116 SUMO1 7341
Co-fractionation Homo sapiens
117 YBX1 4904
Affinity Capture-MS Homo sapiens
118 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
119 PKIG  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 CEP170P1  
Affinity Capture-MS Homo sapiens
121 XRCC6 2547
Affinity Capture-MS Homo sapiens
122 SPP1 6696
Two-hybrid Homo sapiens
123 RYR2 6262
Co-fractionation Homo sapiens
Biochemical Activity Homo sapiens
124 DNA2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
125 PFDN1 5201
Co-fractionation Homo sapiens
126 AVPI1  
Two-hybrid Homo sapiens
127 MAP10  
Affinity Capture-MS Homo sapiens
128 MRPS15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 DFFB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
130 CHD4 1108
Affinity Capture-MS Homo sapiens
131 HSP90AA1 3320
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
132 PRKACA 5566
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 PRKAR2B 5577
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 TF 7018
Affinity Capture-MS Homo sapiens
135 TRAP1 10131
Affinity Capture-MS Homo sapiens
136 APPBP2  
Two-hybrid Homo sapiens
137 TALDO1 6888
Affinity Capture-MS Homo sapiens
138 DDX56  
Affinity Capture-MS Homo sapiens
139 HIST2H3D 653604
Affinity Capture-MS Homo sapiens
140 EEF1A1P5 158078
Cross-Linking-MS (XL-MS) Homo sapiens
141 HIST2H2AA4 723790
Affinity Capture-MS Homo sapiens
142 Mapre1 13589
Affinity Capture-MS Mus musculus
143 ARHGAP36  
Affinity Capture-MS Homo sapiens
144 Prkar2b 19088
Affinity Capture-MS Mus musculus
145 RAPGEF5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 RPS6 6194
Two-hybrid Homo sapiens
147 ARF1 375
Co-fractionation Homo sapiens
148 ZNF641  
Affinity Capture-MS Homo sapiens
149 PDE4DIP 9659
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
150 CCDC96  
Affinity Capture-MS Homo sapiens
151 TIMP3 7078
Affinity Capture-MS Homo sapiens
152 Smn1 20595
Affinity Capture-MS Mus musculus
153 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
154 RANBP2 5903
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PRKACB is involved
PathwayEvidenceSource
Activation of NMDA receptors and postsynaptic events IEA Reactome
Activation of NMDA receptors and postsynaptic events TAS Reactome
Adaptive Immune System TAS Reactome
ADORA2B mediated anti-inflammatory cytokines production IEA Reactome
ADORA2B mediated anti-inflammatory cytokines production TAS Reactome
Anti-inflammatory response favouring Leishmania parasite infection IEA Reactome
Anti-inflammatory response favouring Leishmania parasite infection TAS Reactome
Aquaporin-mediated transport TAS Reactome
Axon guidance IEA Reactome
Axon guidance TAS Reactome
C-type lectin receptors (CLRs) TAS Reactome
Ca-dependent events IEA Reactome
Ca-dependent events TAS Reactome
Calmodulin induced events IEA Reactome
Calmodulin induced events TAS Reactome
CaM pathway IEA Reactome
CaM pathway TAS Reactome
CD209 (DC-SIGN) signaling TAS Reactome
Cellular responses to mechanical stimuli TAS Reactome
Cellular responses to stimuli TAS Reactome
CREB1 phosphorylation through the activation of Adenylate Cyclase IEA Reactome
CREB1 phosphorylation through the activation of Adenylate Cyclase TAS Reactome
DAG and IP3 signaling IEA Reactome
DAG and IP3 signaling TAS Reactome
DARPP-32 events TAS Reactome
Degradation of GLI1 by the proteasome IEA Reactome
Degradation of GLI2 by the proteasome IEA Reactome
Developmental Biology IEA Reactome
Developmental Biology TAS Reactome
Disease IEA Reactome
Disease TAS Reactome
Factors involved in megakaryocyte development and platelet production TAS Reactome
FCGR3A-mediated IL10 synthesis IEA Reactome
FCGR3A-mediated IL10 synthesis TAS Reactome
G alpha (i) signalling events IEA Reactome
G alpha (i) signalling events TAS Reactome
G alpha (s) signalling events IEA Reactome
G alpha (s) signalling events TAS Reactome
G-protein mediated events IEA Reactome
G-protein mediated events TAS Reactome
GLI3 is processed to GLI3R by the proteasome TAS Reactome
Glucagon signaling in metabolic regulation TAS Reactome
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion IEA Reactome
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion TAS Reactome
Glucose metabolism IEA Reactome
Glycolysis IEA Reactome
GPCR downstream signalling IEA Reactome
GPCR downstream signalling TAS Reactome
GPER1 signaling IEA Reactome
GPER1 signaling TAS Reactome
HDL assembly TAS Reactome
Hedgehog 'off' state TAS Reactome
Hedgehog 'off' state IEA Reactome
Hemostasis TAS Reactome
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells TAS Reactome
Immune System TAS Reactome
Infectious disease IEA Reactome
Infectious disease TAS Reactome
Innate Immune System TAS Reactome
Integration of energy metabolism IEA Reactome
Integration of energy metabolism TAS Reactome
Intracellular signaling by second messengers IEA Reactome
Intracellular signaling by second messengers TAS Reactome
Leishmania infection IEA Reactome
Leishmania infection TAS Reactome
Leishmania parasite growth and survival IEA Reactome
Leishmania parasite growth and survival TAS Reactome
MAPK family signaling cascades TAS Reactome
MAPK6/MAPK4 signaling TAS Reactome
Metabolism IEA Reactome
Metabolism TAS Reactome
Metabolism of carbohydrates IEA Reactome
Metabolism of lipids IEA Reactome
Nervous system development IEA Reactome
Nervous system development TAS Reactome
Neuronal System IEA Reactome
Neuronal System TAS Reactome
Neurotransmitter receptors and postsynaptic signal transmission IEA Reactome
Neurotransmitter receptors and postsynaptic signal transmission TAS Reactome
Opioid Signalling IEA Reactome
Opioid Signalling TAS Reactome
Parasitic Infection Pathways IEA Reactome
Parasitic Infection Pathways TAS Reactome
PKA activation TAS Reactome
PKA activation in glucagon signalling TAS Reactome
PKA-mediated phosphorylation of CREB IEA Reactome
PKA-mediated phosphorylation of CREB TAS Reactome
PKA-mediated phosphorylation of key metabolic factors IEA Reactome
Plasma lipoprotein assembly TAS Reactome
Plasma lipoprotein assembly, remodeling, and clearance TAS Reactome
PLC beta mediated events IEA Reactome
PLC beta mediated events TAS Reactome
Post NMDA receptor activation events IEA Reactome
Post NMDA receptor activation events TAS Reactome
Rap1 signalling TAS Reactome
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism IEA Reactome
Regulation of insulin secretion IEA Reactome
Regulation of insulin secretion TAS Reactome
Response of endothelial cells to shear stress TAS Reactome
RET signaling TAS Reactome
ROBO receptors bind AKAP5 IEA Reactome
Signal Transduction IEA Reactome
Signal Transduction TAS Reactome
Signaling by GPCR IEA Reactome
Signaling by GPCR TAS Reactome
Signaling by Hedgehog TAS Reactome
Signaling by Hedgehog IEA Reactome
Signaling by Receptor Tyrosine Kinases TAS Reactome
Signaling by ROBO receptors IEA Reactome
Signaling by VEGF TAS Reactome
Transmission across Chemical Synapses IEA Reactome
Transmission across Chemical Synapses TAS Reactome
Transport of small molecules TAS Reactome
Triglyceride catabolism IEA Reactome
Triglyceride metabolism IEA Reactome
Vasopressin regulates renal water homeostasis via Aquaporins TAS Reactome
VEGFA-VEGFR2 Pathway TAS Reactome





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