Gene description for PRKACB
Gene name	protein kinase, cAMP-dependent, catalytic, beta
Gene symbol	PRKACB
Other names/aliases	PKA C-beta PKACB
Species	Homo sapiens
Database cross references - PRKACB
ExoCarta	ExoCarta_5567
Entrez Gene	5567
HGNC	9381
MIM	176892
UniProt	P22694
PRKACB identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Platelets	25332113
Platelets	25332113
Platelets	25332113
Thymus	23844026

Gene ontology annotations for PRKACB

Molecular Function     cAMP-dependent protein kinase activity GO:0004691 IDA     ubiquitin protein ligase binding GO:0031625 IDA     ATP binding GO:0005524 IDA     protein binding GO:0005515 IPI     magnesium ion binding GO:0000287 IDA Biological Process     regulation of insulin secretion GO:0050796 TAS     water transport GO:0006833 TAS     synaptic transmission GO:0007268 TAS     renal water homeostasis GO:0003091 TAS     protein phosphorylation GO:0006468 IDA     fibroblast growth factor receptor signaling pathway GO:0008543 TAS     negative regulation of meiotic cell cycle GO:0051447 IEA     innate immune response GO:0045087 TAS     response to clozapine GO:0097338 IEA     adenylate cyclase-modulating G-protein coupled receptor signaling pathway GO:0007188 TAS     blood coagulation GO:0007596 TAS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     carbohydrate metabolic process GO:0005975 TAS     energy reserve metabolic process GO:0006112 TAS     negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning GO:1901621 IEA     activation of protein kinase A activity GO:0034199 TAS     regulation of protein processing GO:0070613 IEA     gluconeogenesis GO:0006094 TAS     epidermal growth factor receptor signaling pathway GO:0007173 TAS     cellular response to glucagon stimulus GO:0071377 TAS     transmembrane transport GO:0055085 TAS     triglyceride catabolic process GO:0019433 TAS     glucose metabolic process GO:0006006 TAS     small molecule metabolic process GO:0044281 TAS     signal transduction GO:0007165 TAS     stimulatory C-type lectin receptor signaling pathway GO:0002223 TAS     intracellular signal transduction GO:0035556 TAS     neural tube closure GO:0001843 IEA     activation of phospholipase C activity GO:0007202 TAS Subcellular Localization     plasma membrane GO:0005886 IEA     perinuclear region of cytoplasm GO:0048471 IEA     nucleoplasm GO:0005654 TAS     cytosol GO:0005829 TAS     ciliary base GO:0097546 TAS     centrosome GO:0005813 IDA     extracellular exosome GO:0070062 IDA     cAMP-dependent protein kinase complex GO:0005952 TAS