Gene description for NGFR
Gene name	nerve growth factor receptor
Gene symbol	NGFR
Other names/aliases	CD271 Gp80-LNGFR TNFRSF16 p75(NTR) p75NTR
Species	Homo sapiens
Database cross references - NGFR
ExoCarta	ExoCarta_4804
Entrez Gene	4804
HGNC	7809
MIM	162010
UniProt	P08138
NGFR identified in exosomes derived from the following tissue/cell type
Melanoma cells	25950383

Gene ontology annotations for NGFR

Molecular Function     nerve growth factor binding GO:0048406 IEA     protein binding GO:0005515 IPI     transmembrane signaling receptor activity GO:0004888 TAS     Rab GTPase binding GO:0017137 ISS     death receptor activity GO:0005035 IEA     signal transducer activity GO:0004871 TAS     ubiquitin protein ligase binding GO:0031625 IPI     receptor activity GO:0004872 TAS Biological Process     nerve development GO:0021675 IEA     positive regulation of axonogenesis GO:0050772 TAS     circadian regulation of gene expression GO:0032922 ISS     membrane protein intracellular domain proteolysis GO:0031293 TAS     negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 IEA     negative regulation of hair follicle development GO:0051799 IEA     regulation of glucose import in response to insulin stimulus GO:2001273 ISS     positive regulation of odontogenesis of dentin-containing tooth GO:0042488 IEA     positive regulation of fibroblast proliferation GO:0048146 IEA     glucose homeostasis GO:0042593 ISS     hair follicle morphogenesis GO:0031069 IEA     positive regulation of apoptotic signaling pathway GO:2001235 IEA     detection of temperature stimulus GO:0016048 IEA     negative regulation of apoptotic process GO:0043066 TAS     intracellular protein transport GO:0006886 ISS     regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043281 TAS     regulation of axonogenesis GO:0050770 TAS     negative regulation of cell cycle GO:0045786 TAS     central nervous system development GO:0007417 IEA     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     positive regulation of apoptotic process GO:0043065 TAS     apoptotic signaling pathway GO:0097190 TAS     axon guidance GO:0007411 IEA     negative regulation of axonogenesis GO:0050771 TAS Subcellular Localization     cell surface GO:0009986 ISS     neuronal postsynaptic density GO:0097481 IEA     cytosol GO:0005829 TAS     nucleoplasm GO:0005654 TAS     endosome GO:0005768 TAS     integral component of plasma membrane GO:0005887 TAS     plasma membrane GO:0005886 TAS     extracellular region GO:0005576 TAS