Gene description for NGFR
Gene name	nerve growth factor receptor
Gene symbol	NGFR
Other names/aliases	CD271 Gp80-LNGFR TNFRSF16 p75(NTR) p75NTR
Species	Homo sapiens
Database cross references - NGFR
ExoCarta	ExoCarta_4804
Vesiclepedia	VP_4804
Entrez Gene	4804
HGNC	7809
MIM	162010
UniProt	P08138
NGFR identified in exosomes derived from the following tissue/cell type
Melanocytes	34957415
Melanoma cells	25950383
Melanoma cells	34957415
Melanoma cells	34957415
Melanoma cells	34957415
Melanoma cells	34957415
Melanoma cells	34957415

Gene ontology annotations for NGFR

Molecular Function     nerve growth factor binding GO:0048406 IEA     protein binding GO:0005515 IPI     transmembrane signaling receptor activity GO:0004888 TAS     Rab GTPase binding GO:0017137 ISS     death receptor activity GO:0005035 IEA     signal transducer activity GO:0004871 TAS     ubiquitin protein ligase binding GO:0031625 IPI     receptor activity GO:0004872 TAS Biological Process     nerve development GO:0021675 IEA     positive regulation of axonogenesis GO:0050772 TAS     circadian regulation of gene expression GO:0032922 ISS     membrane protein intracellular domain proteolysis GO:0031293 TAS     negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 IEA     negative regulation of hair follicle development GO:0051799 IEA     regulation of glucose import in response to insulin stimulus GO:2001273 ISS     positive regulation of odontogenesis of dentin-containing tooth GO:0042488 IEA     positive regulation of fibroblast proliferation GO:0048146 IEA     glucose homeostasis GO:0042593 ISS     hair follicle morphogenesis GO:0031069 IEA     positive regulation of apoptotic signaling pathway GO:2001235 IEA     detection of temperature stimulus GO:0016048 IEA     negative regulation of apoptotic process GO:0043066 TAS     intracellular protein transport GO:0006886 ISS     regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043281 TAS     regulation of axonogenesis GO:0050770 TAS     negative regulation of cell cycle GO:0045786 TAS     central nervous system development GO:0007417 IEA     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     positive regulation of apoptotic process GO:0043065 TAS     apoptotic signaling pathway GO:0097190 TAS     axon guidance GO:0007411 IEA     negative regulation of axonogenesis GO:0050771 TAS Subcellular Localization     cell surface GO:0009986 ISS     neuronal postsynaptic density GO:0097481 IEA     cytosol GO:0005829 TAS     nucleoplasm GO:0005654 TAS     endosome GO:0005768 TAS     integral component of plasma membrane GO:0005887 TAS     plasma membrane GO:0005886 TAS     extracellular region GO:0005576 TAS