Gene description for NGFR
Gene name	nerve growth factor receptor
Gene symbol	NGFR
Other names/aliases	CD271 Gp80-LNGFR TNFRSF16 p75(NTR) p75NTR
Species	Homo sapiens
Database cross references - NGFR
ExoCarta	ExoCarta_4804
Vesiclepedia	VP_4804
Entrez Gene	4804
HGNC	7809
MIM	162010
UniProt	P08138
NGFR identified in sEVs derived from the following tissue/cell type
Melanocytes	34957415
Melanoma cells	25950383
Melanoma cells	34957415
Melanoma cells	34957415
Melanoma cells	34957415
Melanoma cells	34957415
Melanoma cells	34957415

Gene ontology annotations for NGFR

Molecular Function     amyloid-beta binding GO:0001540 TAS     transmembrane signaling receptor activity GO:0004888 TAS     death receptor activity GO:0005035 IBA     death receptor activity GO:0005035 IGI     protein binding GO:0005515 IPI     calmodulin binding GO:0005516 IDA     coreceptor activity GO:0015026 IBA     coreceptor activity GO:0015026 IDA     small GTPase binding GO:0031267 ISS     ubiquitin protein ligase binding GO:0031625 IPI     signaling receptor activity GO:0038023 TAS     neurotrophin binding GO:0043121 ISS     nerve growth factor binding GO:0048406 IBA     nerve growth factor binding GO:0048406 ISS Biological Process     intracellular glucose homeostasis GO:0001678 ISS     intracellular protein transport GO:0006886 ISS     Rho protein signal transduction GO:0007266 IBA     Rho protein signal transduction GO:0007266 IDA     axon guidance GO:0007411 IEA     central nervous system development GO:0007417 IEA     fibroblast growth factor receptor signaling pathway GO:0008543 IEA     detection of temperature stimulus GO:0016048 IEA     nerve development GO:0021675 IEA     negative regulation of cell migration GO:0030336 IMP     hair follicle morphogenesis GO:0031069 IEA     circadian regulation of gene expression GO:0032922 ISS     dorsal aorta development GO:0035907 IEA     negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 IEA     odontogenesis of dentin-containing tooth GO:0042475 IEA     positive regulation of odontogenesis of dentin-containing tooth GO:0042488 IEA     glucose homeostasis GO:0042593 ISS     fibroblast proliferation GO:0048144 IEA     positive regulation of fibroblast proliferation GO:0048146 IEA     neuron apoptotic process GO:0051402 IGI     negative regulation of hair follicle development GO:0051799 IEA     extrinsic apoptotic signaling pathway GO:0097191 IDA     presynaptic modulation of chemical synaptic transmission GO:0099171 IEA     positive regulation of protein localization to nucleus GO:1900182 IDA     positive regulation of miRNA transcription GO:1902895 IDA     negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:1903588 IGI     cellular response to amyloid-beta GO:1904646 IDA     positive regulation of endothelial cell apoptotic process GO:2000353 IMP     positive regulation of apoptotic signaling pathway GO:2001235 IEA Subcellular Localization     extracellular region GO:0005576 TAS     nucleoplasm GO:0005654 IDA     nucleoplasm GO:0005654 TAS     endosome GO:0005768 TAS     cytosol GO:0005829 TAS     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     cell-cell junction GO:0005911 IEA     cell surface GO:0009986 IBA     cell surface GO:0009986 ISS     postsynaptic density GO:0014069 IEA     membrane GO:0016020 NAS     growth cone GO:0030426 IEA     neuromuscular junction GO:0031594 IEA     dendritic spine GO:0043197 IEA     perikaryon GO:0043204 IEA     presynapse GO:0098793 IEA