Gene description for TRADD
Gene name	TNFRSF1A-associated via death domain
Gene symbol	TRADD
Other names/aliases	Hs.89862
Species	Homo sapiens
Database cross references - TRADD
ExoCarta	ExoCarta_8717
Entrez Gene	8717
HGNC	12030
MIM	603500
UniProt	Q15628
TRADD identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for TRADD

Molecular Function     kinase binding GO:0019900 IPI     tumor necrosis factor receptor binding GO:0005164 IEA     protein complex binding GO:0032403 IEA     identical protein binding GO:0042802 IPI     signal transducer activity GO:0004871 IEA     death domain binding GO:0070513 IPI     protein binding GO:0005515 IPI     binding, bridging GO:0060090 IPI Biological Process     extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 TAS     apoptotic process GO:0006915 TAS     tumor necrosis factor-mediated signaling pathway GO:0033209 TAS     signal transduction GO:0007165 TAS     necroptotic process GO:0070266 TAS     negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 TAS     death-inducing signaling complex assembly GO:0071550 TAS     positive regulation of apoptotic process GO:0043065 TAS     regulation of necrotic cell death GO:0010939 TAS     activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 TAS     programmed cell death GO:0012501 TAS     cell surface receptor signaling pathway GO:0007166 TAS     programmed necrotic cell death GO:0097300 TAS     positive regulation of NF-kappaB transcription factor activity GO:0051092 TAS     extrinsic apoptotic signaling pathway GO:0097191 TAS     activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 TAS     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 IEP     protein heterooligomerization GO:0051291 IEA     positive regulation of hair follicle development GO:0051798 IEA     regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 TAS Subcellular Localization     receptor complex GO:0043235 IDA     nucleus GO:0005634 IEA     cytoskeleton GO:0005856 IEA     cytoplasm GO:0005737 IDA     cytosol GO:0005829 TAS     membrane raft GO:0045121 IEA     death-inducing signaling complex GO:0031264 TAS