Gene description for Tnfrsf1a
Gene name	tumor necrosis factor receptor superfamily, member 1a
Gene symbol	Tnfrsf1a
Other names/aliases	CD120a FPF TNF-R TNF-R-I TNF-R1 TNF-R55 TNF-alphaR1 TNFAR TNFR60 TNFRI TNFRp55 TNFalpha-R1 Tnfr-2 Tnfr1 p55 p55-R
Species	Mus musculus
Database cross references - Tnfrsf1a
ExoCarta	ExoCarta_21937
Vesiclepedia	VP_21937
Entrez Gene	21937
UniProt	P25118
Tnfrsf1a identified in exosomes derived from the following tissue/cell type
Breast cancer cells	34112803
Breast cancer cells	34112803
Neural stem cells	25242146

Gene ontology annotations for Tnfrsf1a

Molecular Function     protein complex binding GO:0032403 ISO     tumor necrosis factor binding GO:0043120 ISO     protein binding GO:0005515 IPI     tumor necrosis factor-activated receptor activity GO:0005031 TAS     protease binding GO:0002020 ISO Biological Process     tumor necrosis factor-mediated signaling pathway GO:0033209 ISO     positive regulation of inflammatory response GO:0050729 IMP     cytokine-mediated signaling pathway GO:0019221 IMP     inflammatory response GO:0006954 IMP     negative regulation of gene expression GO:0010629 ISO     positive regulation of tumor necrosis factor production GO:0032760 ISO     positive regulation of protein import into nucleus, translocation GO:0033160 ISO     positive regulation of angiogenesis GO:0045766 ISO     signal transduction GO:0007165 IEA     negative regulation of inflammatory response GO:0050728 ISO     programmed cell death GO:0012501 IPI     negative regulation of interleukin-6 production GO:0032715 ISO     negative regulation of apoptotic process GO:0043066 ISO     apoptotic process GO:0006915 IEA     protein heterooligomerization GO:0051291 ISO     regulation of apoptotic process GO:0042981 ISO     positive regulation of tyrosine phosphorylation of Stat1 protein GO:0042511 ISO     intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 IMP     defense response to bacterium GO:0042742 IMP     positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISO     positive regulation of gene expression GO:0010628 ISO     cell surface receptor signaling pathway GO:0007166 IMP     prostaglandin metabolic process GO:0006693 TAS     positive regulation of neuron apoptotic process GO:0043525 ISO     defense response GO:0006952 IMP Subcellular Localization     cytosol GO:0005829 ISO     membrane raft GO:0045121 ISO     Golgi membrane GO:0000139 ISO     extracellular space GO:0005615 ISO     protein complex GO:0043234 ISO     plasma membrane GO:0005886 TAS     Golgi apparatus GO:0005794 IEA     cell surface GO:0009986 ISO     receptor complex GO:0043235 ISO     integral component of membrane GO:0016021 IEA     nucleus GO:0005634 ISO     intracellular GO:0005622 IMP     membrane GO:0016020 IEA     mitochondrion GO:0005739 ISO     synapse GO:0045202 ISO     axon GO:0030424 ISO