Gene description for Ikbkb
Gene name	inhibitor of kappaB kinase beta
Gene symbol	Ikbkb
Other names/aliases	AI132552 IKK-2 IKK-beta IKK2 IKK[b] IKKbeta
Species	Mus musculus
Database cross references - Ikbkb
ExoCarta	ExoCarta_16150
Vesiclepedia	VP_16150
Entrez Gene	16150
UniProt	O88351
Ikbkb identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Ikbkb

Molecular Function     transferase activity, transferring phosphorus-containing groups GO:0016772 IEA     protein serine/threonine kinase activity GO:0004674 IEA     transferase activity GO:0016740 IEA     protein heterodimerization activity GO:0046982 ISO     receptor signaling protein serine/threonine kinase activity GO:0004702 TAS     IkappaB kinase activity GO:0008384 IDA     protein kinase binding GO:0019901 ISO     protein homodimerization activity GO:0042803 ISO     protein kinase activity GO:0004672 ISO     scaffold protein binding GO:0097110 ISO     ATP binding GO:0005524 ISO     kinase activity GO:0016301 IEA     protein binding GO:0005515 IPI     nucleotide binding GO:0000166 IEA Biological Process     positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISO     serine phosphorylation of STAT protein GO:0042501 ISO     positive regulation of cation channel activity GO:2001259 IGI     B cell homeostasis GO:0001782 IMP     signal transduction by protein phosphorylation GO:0023014 TAS     positive regulation of NF-kappaB transcription factor activity GO:0051092 ISO     phosphorylation GO:0016310 IEA     protein phosphorylation GO:0006468 ISO     I-kappaB phosphorylation GO:0007252 TAS     positive regulation of cell proliferation GO:0008284 ISO     positive regulation of neuron death GO:1901216 ISO     positive regulation of sodium ion transport GO:0010765 IGI     neuron projection development GO:0031175 ISO     cellular response to tumor necrosis factor GO:0071356 ISO Subcellular Localization     nucleus GO:0005634 IEA     CD40 receptor complex GO:0035631 IDA     membrane GO:0016020 IEA     IkappaB kinase complex GO:0008385 ISO     cytosol GO:0005829 ISO     intracellular membrane-bounded organelle GO:0043231 ISO     cytoplasmic side of plasma membrane GO:0009898 IDA     cytoplasm GO:0005737 TAS