Gene description for Cd40
Gene name	CD40 antigen
Gene symbol	Cd40
Other names/aliases	AI326936 Bp50 GP39 HIGM1 IGM IMD3 T-BAM TRAP Tnfrsf5 p50
Species	Mus musculus
Database cross references - Cd40
ExoCarta	ExoCarta_21939
Entrez Gene	21939
UniProt	P27512
Cd40 identified in exosomes derived from the following tissue/cell type
Macrophages	23658846
Macrophages	23658846
Macrophages	23658846
Mast cells	11145662

Gene ontology annotations for Cd40

Molecular Function     antigen binding GO:0003823 ISO     enzyme binding GO:0019899 ISO     ubiquitin protein ligase binding GO:0031625 ISO     protein binding GO:0005515 IPI Biological Process     B cell activation GO:0042113 IDA     positive regulation of tyrosine phosphorylation of Stat1 protein GO:0042511 ISO     positive regulation of isotype switching to IgG isotypes GO:0048304 IDA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISO     positive regulation of protein kinase C signaling GO:0090037 ISO     cellular calcium ion homeostasis GO:0006874 ISO     defense response to virus GO:0051607 IDA     positive regulation of endothelial cell apoptotic process GO:2000353 ISO     positive regulation of NF-kappaB transcription factor activity GO:0051092 ISO     positive regulation of GTPase activity GO:0043547 ISO     inflammatory response GO:0006954 ISO     protein kinase B signaling GO:0043491 IDA     positive regulation of MAP kinase activity GO:0043406 ISO     positive regulation of B cell proliferation GO:0030890 IGI     immune system process GO:0002376 IEA     positive regulation of interleukin-12 production GO:0032735 IDA     defense response to protozoan GO:0042832 IDA     immune response-regulating cell surface receptor signaling pathway GO:0002768 IDA     positive regulation of protein phosphorylation GO:0001934 ISO     regulation of immunoglobulin secretion GO:0051023 IDA     regulation of immune response GO:0050776 IDA Subcellular Localization     extracellular exosome GO:0070062 ISO     cell GO:0005623 ISO     membrane GO:0016020 IEA     extracellular region GO:0005576 IEA     intracellular membrane-bounded organelle GO:0043231 IDA     plasma membrane GO:0005886 ISO     cytoplasm GO:0005737 ISO     CD40 receptor complex GO:0035631 ISO     integral component of membrane GO:0016021 IEA     extracellular space GO:0005615 ISO     cell surface GO:0009986 ISO     external side of plasma membrane GO:0009897 IDA