Gene description for FEM1B
Gene name	fem-1 homolog b (C. elegans)
Gene symbol	FEM1B
Other names/aliases	F1A-ALPHA F1AA FEM1-beta
Species	Homo sapiens
Database cross references - FEM1B
ExoCarta	ExoCarta_10116
Vesiclepedia	VP_10116
Entrez Gene	10116
HGNC	3649
MIM	613539
UniProt	Q9UK73
FEM1B identified in exosomes derived from the following tissue/cell type
Endothelial cells	26027894
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for FEM1B

Molecular Function     death receptor binding GO:0005123 IMP     death receptor binding GO:0005123 NAS     protein binding GO:0005515 IPI     metal ion binding GO:0046872 IEA     ubiquitin-like ligase-substrate adaptor activity GO:1990756 IBA     ubiquitin-like ligase-substrate adaptor activity GO:1990756 IDA Biological Process     apoptotic process GO:0006915 NAS     protein ubiquitination GO:0016567 IEA     proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IBA     proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IDA     regulation of ubiquitin-protein transferase activity GO:0051438 IMP     branching involved in prostate gland morphogenesis GO:0060442 IEA     epithelial cell maturation involved in prostate gland development GO:0060743 IEA     ubiquitin-dependent protein catabolic process via the C-end degron rule pathway GO:0140627 IDA     regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 IMP     regulation of DNA damage checkpoint GO:2000001 IMP Subcellular Localization     ubiquitin ligase complex GO:0000151 IBA     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 IDA     cytoplasm GO:0005737 IDA     cytoplasm GO:0005737 IDA     mitochondrion GO:0005739 HTP     cytosol GO:0005829 IDA     cytosol GO:0005829 TAS     Cul2-RING ubiquitin ligase complex GO:0031462 IDA