Gene description for WNT3A
Gene name	wingless-type MMTV integration site family, member 3A
Gene symbol	WNT3A
Other names/aliases	-
Species	Homo sapiens
Database cross references - WNT3A
ExoCarta	ExoCarta_89780
Vesiclepedia	VP_89780
Entrez Gene	89780
HGNC	15983
MIM	606359
UniProt	P56704
WNT3A identified in exosomes derived from the following tissue/cell type
Fibroblasts	33523480

Gene ontology annotations for WNT3A

Molecular Function     frizzled-2 binding GO:0005110 IEA     protein domain specific binding GO:0019904 IEA     transcription coactivator activity GO:0003713 ISS     protein binding GO:0005515 IPI     receptor agonist activity GO:0048018 IDA     frizzled binding GO:0005109 IBA Biological Process     post-anal tail morphogenesis GO:0036342 IEA     negative regulation of heart induction by canonical Wnt signaling pathway GO:0003136 IDA     extracellular matrix organization GO:0030198 IEA     positive regulation of cardiac muscle cell differentiation GO:2000727 IDA     palate development GO:0060021 IMP     hippocampus development GO:0021766 IEA     positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 IEA     positive regulation of cell proliferation GO:0008284 ISS     negative regulation of neurogenesis GO:0050768 ISS     skeletal muscle cell differentiation GO:0035914 IEA     positive regulation of transcription, DNA-templated GO:0045893 ISS     positive regulation of canonical Wnt signaling pathway GO:0090263 TAS     negative regulation of axon extension involved in axon guidance GO:0048843 IEA     positive regulation of dermatome development GO:0061184 IDA     cell proliferation in forebrain GO:0021846 ISS     positive regulation of B cell proliferation GO:0030890 IEA     Wnt signaling pathway involved in forebrain neuroblast division GO:0021874 IEA     mammary gland development GO:0030879 IEA     axon guidance GO:0007411 IEA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA     positive regulation of protein phosphorylation GO:0001934 IDA     cellular response to retinoic acid GO:0071300 ISS     canonical Wnt signaling pathway GO:0060070 IDA     hemopoiesis GO:0030097 IEA     cell fate commitment GO:0045165 IBA     positive regulation of peptidyl-serine phosphorylation GO:0033138 IDA     positive regulation of protein tyrosine kinase activity GO:0061098 IEA     negative regulation of neuron projection development GO:0010977 ISS     negative regulation of fat cell differentiation GO:0045599 IEA     spinal cord association neuron differentiation GO:0021527 IEA     cellular protein localization GO:0034613 IEA     positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 IEA     positive regulation of receptor internalization GO:0002092 IDA     inner ear morphogenesis GO:0042472 IEA     osteoblast differentiation GO:0001649 IEA     positive regulation of cell-cell adhesion mediated by cadherin GO:2000049 IEA     neuron differentiation GO:0030182 ISS     in utero embryonic development GO:0001701 IEA     axis elongation involved in somitogenesis GO:0090245 IEA     positive regulation of mesodermal cell fate specification GO:0048337 IDA     dorsal/ventral neural tube patterning GO:0021904 IEA     regulation of microtubule cytoskeleton organization GO:0070507 IEA     positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation GO:2000081 IEA     positive regulation of collateral sprouting in absence of injury GO:0048697 IEA     positive regulation of neural precursor cell proliferation GO:2000179 IEA     positive regulation of protein binding GO:0032092 IDA     negative regulation of canonical Wnt signaling pathway GO:0090090 TAS     canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 IDA     heart looping GO:0001947 IEA     positive regulation of catenin import into nucleus GO:0035413 IDA     platelet aggregation GO:0070527 IEA     COP9 signalosome assembly GO:0010387 ISS     paraxial mesodermal cell fate commitment GO:0048343 IEA Subcellular Localization     cell surface GO:0009986 ISS     extracellular region GO:0005576 TAS     plasma membrane GO:0005886 TAS     endoplasmic reticulum lumen GO:0005788 TAS     extracellular space GO:0005615 ISS     Golgi lumen GO:0005796 TAS     proteinaceous extracellular matrix GO:0005578 IEA     early endosome membrane GO:0031901 TAS