Gene description for WNT3A
Gene name	wingless-type MMTV integration site family, member 3A
Gene symbol	WNT3A
Other names/aliases	-
Species	Homo sapiens
Database cross references - WNT3A
ExoCarta	ExoCarta_89780
Vesiclepedia	VP_89780
Entrez Gene	89780
HGNC	15983
MIM	606359
UniProt	P56704
WNT3A identified in sEVs derived from the following tissue/cell type
Fibroblasts	33523480

Gene ontology annotations for WNT3A

Molecular Function     transcription coactivator activity GO:0003713 IEA     signaling receptor binding GO:0005102 IPI     frizzled binding GO:0005109 IBA     cytokine activity GO:0005125 IBA     protein binding GO:0005515 IPI     protein domain specific binding GO:0019904 IEA     co-receptor binding GO:0039706 IPI     identical protein binding GO:0042802 IEA     receptor ligand activity GO:0048018 IDA Biological Process     osteoblast differentiation GO:0001649 IEA     in utero embryonic development GO:0001701 IEA     positive regulation of cytokine production GO:0001819 IEA     positive regulation of protein phosphorylation GO:0001934 IDA     heart looping GO:0001947 IEA     positive regulation of receptor internalization GO:0002092 IDA     transcription by RNA polymerase II GO:0006366 IEA     axon guidance GO:0007411 IEA     heart development GO:0007507 IDA     protein localization GO:0008104 IEA     cell population proliferation GO:0008283 IMP     positive regulation of cell population proliferation GO:0008284 ISS     COP9 signalosome assembly GO:0010387 ISS     positive regulation of gene expression GO:0010628 IDA     negative regulation of neuron projection development GO:0010977 ISS     spinal cord association neuron differentiation GO:0021527 IEA     hippocampus development GO:0021766 IEA     cell proliferation in forebrain GO:0021846 ISS     Wnt signaling pathway involved in forebrain neuroblast division GO:0021874 IEA     dorsal/ventral neural tube patterning GO:0021904 IEA     hemopoiesis GO:0030097 IEA     neuron differentiation GO:0030182 IBA     neuron differentiation GO:0030182 ISS     extracellular matrix organization GO:0030198 IEA     mammary gland development GO:0030879 IEA     positive regulation of B cell proliferation GO:0030890 IEA     positive regulation of peptidyl-serine phosphorylation GO:0033138 IDA     cell proliferation in midbrain GO:0033278 TAS     non-canonical Wnt signaling pathway GO:0035567 IEA     skeletal muscle cell differentiation GO:0035914 IEA     post-anal tail morphogenesis GO:0036342 IEA     synaptic vesicle recycling GO:0036465 TAS     B cell proliferation GO:0042100 IEA     inner ear morphogenesis GO:0042472 IEA     cell fate commitment GO:0045165 IBA     fat cell differentiation GO:0045444 IEA     myoblast differentiation GO:0045445 IEA     negative regulation of fat cell differentiation GO:0045599 IEA     positive regulation of DNA-templated transcription GO:0045893 ISS     positive regulation of transcription by RNA polymerase II GO:0045944 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 ISS     somatic stem cell division GO:0048103 IEA     positive regulation of mesodermal cell fate specification GO:0048337 IDA     paraxial mesodermal cell fate commitment GO:0048343 IEA     positive regulation of skeletal muscle tissue development GO:0048643 IEA     positive regulation of collateral sprouting in absence of injury GO:0048697 IEA     negative regulation of axon extension involved in axon guidance GO:0048843 IEA     negative regulation of neurogenesis GO:0050768 ISS     modulation of chemical synaptic transmission GO:0050804 IEA     regulation of synapse organization GO:0050807 IDA     regulation of synapse organization GO:0050807 IMP     canonical Wnt signaling pathway GO:0060070 IBA     canonical Wnt signaling pathway GO:0060070 IDA     canonical Wnt signaling pathway GO:0060070 IMP     canonical Wnt signaling pathway GO:0060070 TAS     cardiac muscle cell fate commitment GO:0060923 IDA     positive regulation of dermatome development GO:0061184 IDA     secondary palate development GO:0062009 IMP     regulation of microtubule cytoskeleton organization GO:0070507 IEA     platelet aggregation GO:0070527 IEA     cellular response to retinoic acid GO:0071300 ISS     axis elongation involved in somitogenesis GO:0090245 IEA     positive regulation of canonical Wnt signaling pathway GO:0090263 IDA     calcium ion transmembrane transport via low voltage-gated calcium channel GO:0090676 IEA     presynapse assembly GO:0099054 TAS     positive regulation of protein localization to plasma membrane GO:1903078 IEA     negative regulation of dopaminergic neuron differentiation GO:1904339 IEA     positive regulation of type B pancreatic cell proliferation GO:1904692 IEA     midbrain dopaminergic neuron differentiation GO:1904948 TAS     regulation of postsynapse to nucleus signaling pathway GO:1905539 IEA     regulation of presynapse assembly GO:1905606 IDA     regulation of presynapse assembly GO:1905606 IMP     positive regulation of cell-cell adhesion mediated by cadherin GO:2000049 IEA     positive regulation of neural precursor cell proliferation GO:2000179 IEA     positive regulation of hepatocyte proliferation GO:2000347 IEA     positive regulation of cardiac muscle cell differentiation GO:2000727 IDA Subcellular Localization     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IBA     extracellular space GO:0005615 IDA     extracellular space GO:0005615 ISS     endoplasmic reticulum lumen GO:0005788 TAS     Golgi lumen GO:0005796 TAS     plasma membrane GO:0005886 TAS     cell surface GO:0009986 ISS     endocytic vesicle membrane GO:0030666 TAS     early endosome membrane GO:0031901 TAS     extracellular exosome GO:0070062 TAS     presynapse GO:0098793 IEA     glutamatergic synapse GO:0098978 IDA     glutamatergic synapse GO:0098978 IMP     Wnt-Frizzled-LRP5/6 complex GO:1990851 IDA