Gene description for BSPRY
Gene name B-box and SPRY domain containing
Gene symbol BSPRY
Other names/aliases -
Species Homo sapiens
 Database cross references - BSPRY
ExoCarta ExoCarta_54836
Vesiclepedia VP_54836
Entrez Gene 54836
HGNC 18232
UniProt Q5W0U4  
 BSPRY identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for BSPRY
Molecular Function
    metal ion binding GO:0046872 IEA
    ubiquitin protein ligase activity GO:0061630 IBA
Biological Process
    calcium ion transport GO:0006816 IEA
    innate immune response GO:0045087 IBA
    cellular response to leukemia inhibitory factor GO:1990830 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    membrane GO:0016020 IEA
    cell leading edge GO:0031252 IEA
    perinuclear region of cytoplasm GO:0048471 IEA
 Experiment description of studies that identified BSPRY in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for BSPRY
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TMF1 7110
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 FAM175B 23172
Affinity Capture-MS Homo sapiens
3 USP4 7375
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 MBLAC2 153364
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 HAUS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 RNF135  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 ADSL 158
Affinity Capture-MS Homo sapiens
8 HSBP1 3281
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 DEAF1 10522
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 MSLN 10232
Affinity Capture-MS Homo sapiens
11 CENPH  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 CUL3 8452
Affinity Capture-MS Homo sapiens
13 CEP55 55165
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 SRGAP2 23380
Affinity Capture-MS Homo sapiens
15 SEMG2 6407
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 ANKRD17 26057
Affinity Capture-MS Homo sapiens
17 PTK2 5747
Affinity Capture-MS Homo sapiens
18 KLHL23  
Affinity Capture-MS Homo sapiens
19 CDK6 1021
Affinity Capture-MS Homo sapiens
20 FEM1B 10116
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 C17orf49 124944
Affinity Capture-MS Homo sapiens
22 MAP2K1 5604
Affinity Capture-MS Homo sapiens
23 SEMG1 6406
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 RUNX1T1  
Affinity Capture-MS Homo sapiens
25 RAB11B 9230
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 CASC5  
Affinity Capture-MS Homo sapiens
27 NCS1 23413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 BTBD9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 OSBPL1A 114876
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 HAUS4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which BSPRY is involved
No pathways found





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