Gene description for BSPRY
Gene name B-box and SPRY domain containing
Gene symbol BSPRY
Other names/aliases -
Species Homo sapiens
 Database cross references - BSPRY
ExoCarta ExoCarta_54836
Entrez Gene 54836
HGNC 18232
UniProt Q5W0U4  
 BSPRY identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for BSPRY
Molecular Function
    zinc ion binding GO:0008270 IEA
Biological Process
    calcium ion transport GO:0006816 IEA
Subcellular Localization
    perinuclear region of cytoplasm GO:0048471 IEA
    focal adhesion GO:0005925 IDA
    membrane GO:0016020 IEA
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IDA
    cell leading edge GO:0031252 IEA
 Experiment description of studies that identified BSPRY in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for BSPRY
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which BSPRY is involved
No pathways found





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