Gene description for TMF1
Gene name TATA element modulatory factor 1
Gene symbol TMF1
Other names/aliases ARA160
TMF
Species Homo sapiens
 Database cross references - TMF1
ExoCarta ExoCarta_7110
Vesiclepedia VP_7110
Entrez Gene 7110
HGNC 11870
MIM 601126
UniProt P82094  
 TMF1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for TMF1
Molecular Function
    protein binding GO:0005515 IPI
    DNA binding GO:0003677 IEA
    transcription cofactor activity GO:0003712 TAS
Biological Process
    spermatid nucleus differentiation GO:0007289 IEA
    defense response to bacterium GO:0042742 IEA
    luteinizing hormone secretion GO:0032275 IEA
    positive regulation of testosterone secretion GO:2000845 IEA
    negative regulation of apoptotic process GO:0043066 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
    transcription from RNA polymerase II promoter GO:0006366 TAS
    positive regulation of cytokine production GO:0001819 IEA
    regulation of proteasomal protein catabolic process GO:0061136 ISS
    Leydig cell differentiation GO:0033327 IEA
    sperm motility GO:0030317 IEA
    cellular response to organic cyclic compound GO:0071407 IEA
    acrosome assembly GO:0001675 IEA
    negative regulation of gene expression GO:0010629 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    Golgi membrane GO:0000139 IEA
    endoplasmic reticulum GO:0005783 IEA
    Golgi apparatus GO:0005794 IDA
 Experiment description of studies that identified TMF1 in exosomes
1
Experiment ID 217
MISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|CD81|CD9|CD63
EV Enriched markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TMF1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 AR 367
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
2 FER 2241
Invitro Homo sapiens
Invivo Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which TMF1 is involved
No pathways found





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