Gene description for TNFRSF1A
Gene name	tumor necrosis factor receptor superfamily, member 1A
Gene symbol	TNFRSF1A
Other names/aliases	CD120a FPF MS5 TBP1 TNF-R TNF-R-I TNF-R55 TNFAR TNFR1 TNFR1-d2 TNFR55 TNFR60 p55 p55-R p60
Species	Homo sapiens
Database cross references - TNFRSF1A
ExoCarta	ExoCarta_7132
Entrez Gene	7132
HGNC	11916
MIM	191190
UniProt	P19438
TNFRSF1A identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for TNFRSF1A

Molecular Function     tumor necrosis factor-activated receptor activity GO:0005031 TAS     protein binding GO:0005515 IPI     protein complex binding GO:0032403 IEA     tumor necrosis factor binding GO:0043120 IEA     protease binding GO:0002020 IEA Biological Process     viral process GO:0016032 IEA     cellular response to mechanical stimulus GO:0071260 IEP     tumor necrosis factor-mediated signaling pathway GO:0033209 TAS     cellular response to estradiol stimulus GO:0071392 IEA     cell surface receptor signaling pathway GO:0007166 TAS     prostaglandin metabolic process GO:0006693 IEA     response to ethanol GO:0045471 IEA     intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 IEA     defense response to bacterium GO:0042742 IEA     positive regulation of tyrosine phosphorylation of Stat1 protein GO:0042511 IMP     positive regulation of protein import into nucleus, translocation GO:0033160 IEA     negative regulation of gene expression GO:0010629 IEA     positive regulation of angiogenesis GO:0045766 IEA     response to lipopolysaccharide GO:0032496 IEA     response to wounding GO:0009611 IEA     extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 TAS     response to hypoxia GO:0001666 IEA     protein heterooligomerization GO:0051291 IEA     inflammatory response GO:0006954 ISS     response to amino acid GO:0043200 IEA     response to alkaloid GO:0043279 IEA     tetrapyrrole metabolic process GO:0033013 IEA     death-inducing signaling complex assembly GO:0071550 TAS     negative regulation of inflammatory response GO:0050728 IMP     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 IEP     positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISS     negative regulation of apoptotic process GO:0043066 IEA     positive regulation of tumor necrosis factor production GO:0032760 IEA     cytokine-mediated signaling pathway GO:0019221 ISS     negative regulation of interleukin-6 production GO:0032715 IEA     positive regulation of neuron apoptotic process GO:0043525 IEA     positive regulation of inflammatory response GO:0050729 ISS Subcellular Localization     cell surface GO:0009986 IEA     nucleus GO:0005634 IEA     receptor complex GO:0043235 IDA     membrane raft GO:0045121 IDA     synapse GO:0045202 IEA     extracellular region GO:0005576 NAS     plasma membrane GO:0005886 TAS     cytosol GO:0005829 IEA     mitochondrion GO:0005739 IEA     axon GO:0030424 IEA     integral component of plasma membrane GO:0005887 TAS     Golgi membrane GO:0000139 IDA     extracellular space GO:0005615 IDA