Gene description for UBQLN1
Gene name ubiquilin 1
Gene symbol UBQLN1
Other names/aliases DA41
DSK2
PLIC-1
UBQN
XDRP1
Species Homo sapiens
 Database cross references - UBQLN1
ExoCarta ExoCarta_29979
Vesiclepedia VP_29979
Entrez Gene 29979
HGNC 12508
MIM 605046
UniProt Q9UMX0  
 UBQLN1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
 Gene ontology annotations for UBQLN1
Molecular Function
    protein binding GO:0005515 IPI
    kinase binding GO:0019900 IPI
    polyubiquitin modification-dependent protein binding GO:0031593 IBA
    polyubiquitin modification-dependent protein binding GO:0031593 IDA
    identical protein binding GO:0042802 IPI
Biological Process
    autophagosome assembly GO:0000045 IBA
    autophagosome assembly GO:0000045 IMP
    ubiquitin-dependent protein catabolic process GO:0006511 IBA
    macroautophagy GO:0016236 IMP
    regulation of macroautophagy GO:0016241 IBA
    regulation of protein ubiquitination GO:0031396 IDA
    positive regulation of protein ubiquitination GO:0031398 IDA
    negative regulation of toll-like receptor 3 signaling pathway GO:0034140 IEA
    response to endoplasmic reticulum stress GO:0034976 IMP
    aggrephagy GO:0035973 IDA
    ERAD pathway GO:0036503 IBA
    ERAD pathway GO:0036503 IMP
    cellular response to hypoxia GO:0071456 IMP
    autophagosome maturation GO:0097352 IMP
    negative regulation of store-operated calcium channel activity GO:1901340 IMP
    regulation of oxidative stress-induced intrinsic apoptotic signaling pathway GO:1902175 IMP
    positive regulation of ERAD pathway GO:1904294 IMP
Subcellular Localization
    proteasome complex GO:0000502 IEA
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 IMP
    autophagosome GO:0005776 IBA
    autophagosome GO:0005776 IDA
    endoplasmic reticulum GO:0005783 IDA
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    plasma membrane GO:0005886 IDA
    aggresome GO:0016235 IDA
    cytoplasmic vesicle GO:0031410 IEA
    protein-containing complex GO:0032991 IDA
    perinuclear region of cytoplasm GO:0048471 IDA
    perinuclear region of cytoplasm GO:0048471 NAS
 Experiment description of studies that identified UBQLN1 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for UBQLN1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
2 PSMA6 5687
Affinity Capture-Western Homo sapiens
3 ZMYM5 9205
Two-hybrid Homo sapiens
4 ACOT7 11332
Two-hybrid Homo sapiens
5 MCM7 4176
Two-hybrid Homo sapiens
6 MESDC2 23184
Two-hybrid Homo sapiens
7 BPIFA1 51297
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
8 ZG16  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
9 CBX1 10951
Affinity Capture-MS Homo sapiens
10 SLC5A10 125206
Affinity Capture-MS Homo sapiens
11 UBE2A  
Co-fractionation Homo sapiens
12 CCL3  
Two-hybrid Homo sapiens
13 CD99 4267
Two-hybrid Homo sapiens
14 PSMD6 9861
Two-hybrid Homo sapiens
15 PSMD3 5709
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
16 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
17 PIK3IP1 113791
Two-hybrid Homo sapiens
18 TRIAP1  
Co-fractionation Homo sapiens
19 TARDBP 23435
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
20 GIT2 9815
Two-hybrid Homo sapiens
21 FBXO25  
Biochemical Activity Homo sapiens
22 DNAJB2 3300
Reconstituted Complex Homo sapiens
23 CYB5R1 51706
Two-hybrid Homo sapiens
24 HSPA13 6782
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
25 HSPA1L 3305
Co-fractionation Homo sapiens
26 EPS15 2060
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
27 RELA 5970
Affinity Capture-Western Homo sapiens
28 UBE3A 7337
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
29 ZDHHC4  
Affinity Capture-MS Homo sapiens
30 UBC 7316
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
31 NDOR1  
Two-hybrid Homo sapiens
32 RIC8A 60626
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
33 RSRC2  
Two-hybrid Homo sapiens
34 LNPEP 4012
Two-hybrid Homo sapiens
35 TXNDC12 51060
Two-hybrid Homo sapiens
36 TMUB2  
Two-hybrid Homo sapiens
37 PRPF40A 55660
Two-hybrid Homo sapiens
38 MANBAL 63905
Two-hybrid Homo sapiens
39 RNF208  
Two-hybrid Homo sapiens
40 HSD17B12 51144
Two-hybrid Homo sapiens
41 OR4N2  
Affinity Capture-MS Homo sapiens
42 PSEN2 5664
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
43 KDELR1 10945
Affinity Capture-MS Homo sapiens
44 VPS26A 9559
Co-fractionation Homo sapiens
45 AGR3 155465
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
46 IL6ST 3572
Two-hybrid Homo sapiens
47 GABRA1  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
48 MINOS1-NBL1  
Two-hybrid Homo sapiens
49 NDE1 54820
Two-hybrid Homo sapiens
50 HRASLS  
Two-hybrid Homo sapiens
51 NUBP1 4682
Co-fractionation Homo sapiens
52 AGPAT5 55326
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
53 OR6T1  
Affinity Capture-MS Homo sapiens
54 CARKD 55739
Two-hybrid Homo sapiens
55 RNF144B  
Two-hybrid Homo sapiens
56 GRM2 2912
Two-hybrid Homo sapiens
57 SMR3B  
Two-hybrid Homo sapiens
58 CTAG1A  
Two-hybrid Homo sapiens
59 GKAP1  
Two-hybrid Homo sapiens
60 HGS 9146
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
61 LAIR2  
Two-hybrid Homo sapiens
62 UBL4A 8266
Affinity Capture-MS Homo sapiens
63 C1QTNF4  
Two-hybrid Homo sapiens
64 PARVA 55742
Two-hybrid Homo sapiens
65 GPR162  
Two-hybrid Homo sapiens
66 DCTPP1 79077
Co-fractionation Homo sapiens
67 TNFAIP3 7128
Two-hybrid Homo sapiens
68 NT5C3A 51251
Two-hybrid Homo sapiens
69 PSMC2 5701
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
70 UBQLN1 29979
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
71 EPS15L1 58513
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
72 DYNLL1 8655
Affinity Capture-MS Homo sapiens
73 GABRB3 2562
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
74 CHGB 1114
Two-hybrid Homo sapiens
75 MLLT6  
Two-hybrid Homo sapiens
76 EDEM1  
Affinity Capture-MS Homo sapiens
77 UCHL5 51377
Affinity Capture-MS Homo sapiens
78 GUCA2A  
Two-hybrid Homo sapiens
79 NGLY1 55768
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
80 COLGALT2  
Two-hybrid Homo sapiens
81 ABCC2 1244
Two-hybrid Homo sapiens
82 CD3D 915
Affinity Capture-Western Homo sapiens
83 GABRA6  
Two-hybrid Homo sapiens
84 WBP2 23558
Two-hybrid Homo sapiens
85 FZD7 8324
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
86 UBQLN4 56893
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
87 TNFRSF1B  
Two-hybrid Homo sapiens
88 FAM20C 56975
Affinity Capture-MS Homo sapiens
89 COMTD1 118881
Two-hybrid Homo sapiens
90 RAD23A 5886
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
91 SMIM2  
Two-hybrid Homo sapiens
92 SLPI 6590
Two-hybrid Homo sapiens
93 C5orf56  
Two-hybrid Homo sapiens
94 FAS 355
Two-hybrid Homo sapiens
95 WDR1 9948
Co-fractionation Homo sapiens
96 APOC4  
Two-hybrid Homo sapiens
97 INSIG2  
Affinity Capture-MS Homo sapiens
98 UBE2V1 7335
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
99 UNK  
Co-fractionation Homo sapiens
100 WWP2 11060
Biochemical Activity Homo sapiens
101 H2AFZ 3015
Affinity Capture-MS Homo sapiens
102 STAM2 10254
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
103 PRAP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
104 RAD23B 5887
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
105 TREX1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
106 PPIB 5479
Two-hybrid Homo sapiens
107 UBE4B 10277
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
108 GABRA2  
Two-hybrid Homo sapiens
109 APOC2 344
Two-hybrid Homo sapiens
110 PSMD4 5710
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
111 SLC29A2 3177
Two-hybrid Homo sapiens
112 GABRA3  
Two-hybrid Homo sapiens
113 CSTF2 1478
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
114 CLNS1A 1207
Co-fractionation Homo sapiens
115 DEFB115  
Two-hybrid Homo sapiens
116 SPARC 6678
Two-hybrid Homo sapiens
117 PSMD14 10213
Affinity Capture-MS Homo sapiens
118 GABRB1  
Two-hybrid Homo sapiens
119 GHRL  
Two-hybrid Homo sapiens
120 HTT 3064
Affinity Capture-Western Homo sapiens
121 UBXN7 26043
Two-hybrid Homo sapiens
122 ASCL1  
Two-hybrid Homo sapiens
123 UBE2I 7329
Two-hybrid Homo sapiens
124 TLR4  
Two-hybrid Homo sapiens
125 JSRP1  
Two-hybrid Homo sapiens
126 SLC16A3 9123
Two-hybrid Homo sapiens
127 UBXN1 51035
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
128 PBXIP1 57326
Two-hybrid Homo sapiens
129 PSMD2 5708
Co-fractionation Homo sapiens
130 SCG2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
131 VCP 7415
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
132 NTRK1 4914
Affinity Capture-MS Homo sapiens
133 SCG5  
Two-hybrid Homo sapiens
134 NPY  
Two-hybrid Homo sapiens
135 TMEM258  
Two-hybrid Homo sapiens
136 ATP6V1B2 526
Co-fractionation Homo sapiens
137 CCL7 6354
Two-hybrid Homo sapiens
138 PCDHA4 56144
Two-hybrid Homo sapiens
139 TRIM32 22954
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
140 AGR2 10551
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
141 NME3 4832
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
142 C12orf10 60314
Co-fractionation Homo sapiens
143 RPN1 6184
Two-hybrid Homo sapiens
144 TFF1 7031
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
145 FAM127C  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
146 DYNLL2 140735
Affinity Capture-MS Homo sapiens
147 FAM127A  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
148 OST4  
Two-hybrid Homo sapiens
149 IGL 3535
Two-hybrid Homo sapiens
150 GPX3 2878
Two-hybrid Homo sapiens
151 F8 2157
Two-hybrid Homo sapiens
152 CYLD  
Affinity Capture-MS Homo sapiens
153 WDFY1 57590
Co-fractionation Homo sapiens
154 HERPUD1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
155 YAP1 10413
Affinity Capture-MS Homo sapiens
156 FAM127B  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
157 ZMYM4  
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
158 FAM163B  
Two-hybrid Homo sapiens
159 PDCD6 10016
Co-fractionation Homo sapiens
160 PTN  
Two-hybrid Homo sapiens
161 C1QTNF2  
Two-hybrid Homo sapiens
162 SPAG8  
Two-hybrid Homo sapiens
163 MIEF1  
Two-hybrid Homo sapiens
164 RAP1GDS1 5910
Co-fractionation Homo sapiens
165 NUPL1 9818
Two-hybrid Homo sapiens
166 PSEN1 5663
FRET Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
167 VPS4B 9525
Co-fractionation Homo sapiens
168 AHCYL1 10768
Co-fractionation Homo sapiens
169 CSTF2T  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
170 DMKN  
Two-hybrid Homo sapiens
171 SAR1B 51128
Affinity Capture-MS Homo sapiens
172 SLC45A4  
Affinity Capture-MS Homo sapiens
173 TMEM37  
Two-hybrid Homo sapiens
174 USP9X 8239
Co-fractionation Homo sapiens
175 C1QA 712
Two-hybrid Homo sapiens
176 UBQLN2 29978
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
177 SOD3 6649
Two-hybrid Homo sapiens
178 TRIM23 373
Two-hybrid Homo sapiens
179 HYPK 25764
Co-fractionation Homo sapiens
180 TNFRSF1A 7132
Two-hybrid Homo sapiens
181 TMCO6  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
182 ORAI1 84876
Affinity Capture-Western Homo sapiens
183 NPPA  
Two-hybrid Homo sapiens
184 MTNR1A  
Two-hybrid Homo sapiens
185 RBMS1 5937
Co-fractionation Homo sapiens
186 SERPINE1 5054
Two-hybrid Homo sapiens
187 MAP3K1 4214
Biochemical Activity Homo sapiens
188 CTAG2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
189 ITPRIPL1  
Two-hybrid Homo sapiens
190 WIBG 84305
Co-fractionation Homo sapiens
191 UBE2C 11065
Co-fractionation Homo sapiens
192 FN1 2335
Two-hybrid Homo sapiens
193 NXF1 10482
Two-hybrid Homo sapiens
194 UBE2D2 7322
Co-fractionation Homo sapiens
195 XPO4 64328
Two-hybrid Homo sapiens
196 PRR4 11272
Two-hybrid Homo sapiens
197 IST1 9798
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
198 PRB1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
199 SMAD9  
Two-hybrid Homo sapiens
200 HRASLS2  
Two-hybrid Homo sapiens
201 P4HB 5034
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
202 MTOR 2475
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
203 PLA2G16 11145
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
204 MTHFD1 4522
Co-fractionation Homo sapiens
205 COL10A1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
206 UBL7  
Co-fractionation Homo sapiens
207 STMN1 3925
Co-fractionation Homo sapiens
208 CHRNB2  
Affinity Capture-MS Homo sapiens
209 GYPB  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
210 SMIM19  
Two-hybrid Homo sapiens
211 SCMH1  
Two-hybrid Homo sapiens
212 RNF185  
Affinity Capture-MS Homo sapiens
213 GABRD  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
214 IGLC1 3537
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
215 GNPDA1 10007
Co-fractionation Homo sapiens
216 VWC2  
Two-hybrid Homo sapiens
217 APP 351
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
FRET Homo sapiens
218 UBA52 7311
Two-hybrid Homo sapiens
219 TICAM1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
220 ACBD5 91452
Proximity Label-MS Homo sapiens
221 LCN2 3934
Two-hybrid Homo sapiens
222 UBE2D1 7321
Co-fractionation Homo sapiens
223 ATP6V1H 51606
Co-fractionation Homo sapiens
224 HK2 3099
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
225 RAI2  
Two-hybrid Homo sapiens
226 ZRANB2 9406
Co-fractionation Homo sapiens
227 PPIC 5480
Two-hybrid Homo sapiens
228 RPS27A 6233
Two-hybrid Homo sapiens
229 RARA 5914
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
230 ETNK1  
Two-hybrid Homo sapiens
231 UBXN4 23190
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
232 ATXN3 4287
Reconstituted Complex Homo sapiens
233 NBL1 4681
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
234 SRGN 5552
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
235 USP34 9736
Co-fractionation Homo sapiens
236 MDK 4192
Two-hybrid Homo sapiens
237 ASNS 440
Co-fractionation Homo sapiens
238 CALU 813
Two-hybrid Homo sapiens
239 CTAG1B  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
240 DEXI  
Two-hybrid Homo sapiens
241 IER3IP1 51124
Two-hybrid Homo sapiens
242 FAM86B3P  
Two-hybrid Homo sapiens
243 CD47 961
Affinity Capture-Western Homo sapiens
244 CDSN 1041
Two-hybrid Homo sapiens
245 DAZAP2  
Two-hybrid Homo sapiens
246 LITAF 9516
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
247 SMURF1 57154
Biochemical Activity Homo sapiens
248 SIL1 64374
Two-hybrid Homo sapiens
249 SHFM1 7979
Affinity Capture-MS Homo sapiens
250 PSORS1C2  
Two-hybrid Homo sapiens
251 FCGR2A 2212
Two-hybrid Homo sapiens
252 PNMA1 9240
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
253 GNB1 2782
Affinity Capture-Western Homo sapiens
254 UCHL3 7347
Co-fractionation Homo sapiens
255 ZMYM3  
Co-fractionation Homo sapiens
256 SERPINI2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
257 SFXN1 94081
Co-fractionation Homo sapiens
258 RASSF5 83593
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
259 KLHL42  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
260 COL1A2 1278
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
261 UBB 7314
Two-hybrid Homo sapiens
262 FOLR3  
Two-hybrid Homo sapiens
263 CEBPA  
Protein-peptide Homo sapiens
264 MAP1LC3A 84557
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
265 GAPDH 2597
Co-fractionation Homo sapiens
266 PSMA5 5686
Co-fractionation Homo sapiens
267 UBE2B 7320
Co-fractionation Homo sapiens
268 BAG6 7917
Two-hybrid Homo sapiens
269 SNRNP70 6625
Co-fractionation Homo sapiens
270 PSMA7 5688
Affinity Capture-Western Homo sapiens
271 PCDH18 54510
Two-hybrid Homo sapiens
272 ZG16B 124220
Two-hybrid Homo sapiens
273 SSSCA1 10534
Co-fractionation Homo sapiens
274 BCL2L10  
Affinity Capture-Western Homo sapiens
275 HERC3 8916
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
276 DEFA6  
Two-hybrid Homo sapiens
277 STMN3  
Two-hybrid Homo sapiens
278 FAM189A2  
Two-hybrid Homo sapiens
279 CD99L2 83692
Two-hybrid Homo sapiens
280 WFDC12  
Two-hybrid Homo sapiens
281 GABRB2 2561
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
282 ZNF343  
Two-hybrid Homo sapiens
283 ADRM1 11047
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
284 ECM1 1893
Two-hybrid Homo sapiens
285 TMEM31  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
286 IGFBP6 3489
Two-hybrid Homo sapiens
287 FGF7  
Two-hybrid Homo sapiens
288 EFEMP2 30008
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
289 PSMC4 5704
Affinity Capture-MS Homo sapiens
290 ERP27  
Two-hybrid Homo sapiens
291 FKBP2 2286
Two-hybrid Homo sapiens
292 MIEF2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
293 ZBTB8B  
Two-hybrid Homo sapiens
294 NEDD8 4738
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
295 EP300 2033
Two-hybrid Homo sapiens
296 CSN3 1448
Two-hybrid Homo sapiens
297 IGLV2-14  
Two-hybrid Homo sapiens
298 ZFAND2B  
Two-hybrid Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here