Gene description for UBQLN1
Gene name
ubiquilin 1
Gene symbol
UBQLN1
Other names/aliases
DA41 DSK2 PLIC-1 UBQN XDRP1
Species
Homo sapiens
Database cross references - UBQLN1
ExoCarta
ExoCarta_29979
Entrez Gene
29979
HGNC
12508
MIM
605046
UniProt
Q9UMX0
UBQLN1 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Gene ontology annotations for UBQLN1
Experiment description of studies that identified UBQLN1 in exosomes
1
Experiment ID
211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for UBQLN1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
FZD7
8324
Two-hybrid
Homo sapiens
2
KLHDC5
Two-hybrid
Homo sapiens
3
CD99
4267
Two-hybrid
Homo sapiens
4
NBL1
4681
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
5
DKFZP564B147
Two-hybrid
Homo sapiens
6
CSTF2T
Two-hybrid
Homo sapiens
7
SMCR7
Two-hybrid
Homo sapiens
8
HSPA13
6782
Two-hybrid
Homo sapiens
9
GABRD
Two-hybrid
Homo sapiens
10
PRO1580
Two-hybrid
Homo sapiens
11
RIC8A
60626
Two-hybrid
Homo sapiens
12
PRPF40A
55660
Affinity Capture-MS
Homo sapiens
13
PSEN2
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
14
SMAD9
Affinity Capture-MS
Homo sapiens
15
HK2
Two-hybrid
Homo sapiens
16
MTOR
2475
Two-hybrid
Homo sapiens
Invitro
Homo sapiens
Invivo
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
17
PLA2G16
11145
Two-hybrid
Homo sapiens
18
TRIM32
22954
Two-hybrid
Homo sapiens
19
P4HB
5034
Affinity Capture-MS
Homo sapiens
Invitro
Homo sapiens
Invivo
Homo sapiens
Two-hybrid
Homo sapiens
20
HGS
9146
Two-hybrid
Homo sapiens
21
TFF1
7031
Two-hybrid
Homo sapiens
22
SERPINI2
Two-hybrid
Homo sapiens
23
UBQLN1
29979
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
24
IGLC1
3537
Two-hybrid
Homo sapiens
25
CSTF2
Two-hybrid
Homo sapiens
26
PSEN1
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
27
EFEMP2
30008
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which UBQLN1 is involved
No pathways found