Gene description for SLC5A10
Gene name solute carrier family 5 (sodium/sugar cotransporter), member 10
Gene symbol SLC5A10
Other names/aliases SGLT-5
SGLT5
Species Homo sapiens
 Database cross references - SLC5A10
ExoCarta ExoCarta_125206
Vesiclepedia VP_125206
Entrez Gene 125206
HGNC 23155
UniProt A0PJK1  
 SLC5A10 identified in sEVs derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for SLC5A10
Molecular Function
    D-glucose:sodium symporter activity GO:0005412 IBA
    solute:sodium symporter activity GO:0015370 TAS
    mannose:sodium symporter activity GO:0140929 IDA
    mannose:sodium symporter activity GO:0140929 IEA
    fructose:sodium symporter activity GO:0140930 IDA
    fructose:sodium symporter activity GO:0140930 IEA
Biological Process
    hexose transmembrane transport GO:0008645 TAS
    fructose transmembrane transport GO:0015755 IEA
    mannose transmembrane transport GO:0015761 IEA
    sodium ion transmembrane transport GO:0035725 IEA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 TAS
    apical plasma membrane GO:0016324 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified SLC5A10 in sEVs
1
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SLC5A10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBQLN4 56893
Affinity Capture-MS Homo sapiens
2 UBQLN1 29979
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SLC5A10 is involved
PathwayEvidenceSource
Cellular hexose transport TAS Reactome
SLC-mediated transmembrane transport TAS Reactome
Transport of small molecules TAS Reactome





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