Gene description for ZMYM5
Gene name zinc finger, MYM-type 5
Gene symbol ZMYM5
Other names/aliases HSPC050
MYM
ZNF198L1
ZNF237
Species Homo sapiens
 Database cross references - ZMYM5
ExoCarta ExoCarta_9205
Vesiclepedia VP_9205
Entrez Gene 9205
HGNC 13029
UniProt Q9UJ78  
 ZMYM5 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for ZMYM5
Molecular Function
    protein binding GO:0005515 IPI
    zinc ion binding GO:0008270 IEA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IDA
Subcellular Localization
    nucleus GO:0005634 IEA
 Experiment description of studies that identified ZMYM5 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ZMYM5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CBS 875
Two-hybrid Homo sapiens
2 RPS6KA2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 FADD 8772
Two-hybrid Homo sapiens
4 TRAF2 7186
Two-hybrid Homo sapiens
5 CARD9 64170
Two-hybrid Homo sapiens
6 ACAD11 84129
Affinity Capture-MS Homo sapiens
7 ZBTB26  
Two-hybrid Homo sapiens
8 DES 1674
Two-hybrid Homo sapiens
9 HMBOX1  
Two-hybrid Homo sapiens
10 HOMER1  
Two-hybrid Homo sapiens
11 APP 351
Reconstituted Complex Homo sapiens
12 TFG 10342
Two-hybrid Homo sapiens
13 PAX5  
Two-hybrid Homo sapiens
14 RPS6KA3 6197
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 PCK1 5105
Affinity Capture-MS Homo sapiens
16 SSSCA1 10534
Two-hybrid Homo sapiens
17 SUMO2 6613
Two-hybrid Homo sapiens
18 PML 5371
Affinity Capture-MS Homo sapiens
19 UBQLN1 29979
Two-hybrid Homo sapiens
20 PRMT1 3276
Two-hybrid Homo sapiens
21 LCE3B  
Two-hybrid Homo sapiens
22 SUMO1 7341
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
23 LOC102724560 102724560
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ZMYM5 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here