Gene description for CARD9
Gene name	caspase recruitment domain family, member 9
Gene symbol	CARD9
Other names/aliases	CANDF2 hCARD9
Species	Homo sapiens
Database cross references - CARD9
ExoCarta	ExoCarta_64170
Vesiclepedia	VP_64170
Entrez Gene	64170
HGNC	16391
MIM	607212
UniProt	Q9H257
CARD9 identified in exosomes derived from the following tissue/cell type
Prostate cancer cells	25844599

Gene ontology annotations for CARD9

Molecular Function     protein binding GO:0005515 IPI     signaling adaptor activity GO:0035591 IDA     identical protein binding GO:0042802 IPI     protein homodimerization activity GO:0042803 IPI     metal ion binding GO:0046872 IEA     CARD domain binding GO:0050700 IPI Biological Process     positive regulation of cytokine production GO:0001819 IMP     neutrophil mediated immunity GO:0002446 IMP     JNK cascade GO:0007254 IEA     response to xenobiotic stimulus GO:0009410 IEA     immunoglobulin mediated immune response GO:0016064 IMP     response to peptidoglycan GO:0032494 IEA     response to muramyl dipeptide GO:0032495 IEA     regulation of interleukin-2 production GO:0032663 IEA     positive regulation of chemokine production GO:0032722 IEA     positive regulation of granulocyte macrophage colony-stimulating factor production GO:0032725 IMP     positive regulation of interleukin-17 production GO:0032740 IMP     positive regulation of interleukin-6 production GO:0032755 IMP     positive regulation of tumor necrosis factor production GO:0032760 IEA     positive regulation of stress-activated MAPK cascade GO:0032874 IDA     positive regulation of stress-activated MAPK cascade GO:0032874 ISS     regulation of apoptotic process GO:0042981 IEA     positive regulation of canonical NF-kappaB signal transduction GO:0043123 IBA     positive regulation of canonical NF-kappaB signal transduction GO:0043123 IDA     positive regulation of canonical NF-kappaB signal transduction GO:0043123 IEP     response to exogenous dsRNA GO:0043330 IEA     positive regulation of innate immune response GO:0045089 IEA     positive regulation of JNK cascade GO:0046330 IDA     host-mediated regulation of intestinal microbiota composition GO:0048874 IMP     regulation of immune response GO:0050776 IBA     defense response to Gram-positive bacterium GO:0050830 IEA     positive regulation of NF-kappaB transcription factor activity GO:0051092 IDA     positive regulation of NF-kappaB transcription factor activity GO:0051092 IMP     protein homooligomerization GO:0051260 IDA     stress-activated MAPK cascade GO:0051403 IEA     defense response to virus GO:0051607 IEA     positive regulation of macrophage cytokine production GO:0060907 IEA     antifungal innate immune response GO:0061760 IDA     antifungal innate immune response GO:0061760 IMP     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISS     apoptotic signaling pathway GO:0097190 IMP     positive regulation of cytokine production involved in inflammatory response GO:1900017 ISS     response to aldosterone GO:1904044 IEA     positive regulation of T-helper 17 type immune response GO:2000318 IMP Subcellular Localization     cytoplasm GO:0005737 IDA     cytoplasm GO:0005737 IDA     cytosol GO:0005829 TAS     plasma membrane GO:0005886 TAS     CBM complex GO:0032449 IBA     protein-containing complex GO:0032991 IDA