Gene description for GSTT2B
Gene name glutathione S-transferase theta 2B (gene/pseudogene)
Gene symbol GSTT2B
Other names/aliases GSTT2P
Species Homo sapiens
 Database cross references - GSTT2B
ExoCarta ExoCarta_653689
Vesiclepedia VP_653689
Entrez Gene 653689
HGNC 33437
UniProt P0CG30  
 GSTT2B identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for GSTT2B
Molecular Function
    glutathione transferase activity GO:0004364 IBA
    glutathione transferase activity GO:0004364 IDA
    glutathione transferase activity GO:0004364 NAS
    protein binding GO:0005515 IPI
Biological Process
    glutathione metabolic process GO:0006749 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified GSTT2B in sEVs
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for GSTT2B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GSTP1 2950
Co-fractionation Homo sapiens
2 CARD9 64170
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 NMD3 51068
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
5 NFRKB  
Co-fractionation Homo sapiens
6 RPA3 6119
Proximity Label-MS Homo sapiens
7 SPDL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 SIRT2 22933
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which GSTT2B is involved
PathwayEvidenceSource
Biological oxidations TAS Reactome
Glutathione conjugation TAS Reactome
Metabolism TAS Reactome
Phase II - Conjugation of compounds TAS Reactome





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