Experiment description of studies that identified SIRT2 in exosomes

1 Experiment ID 237 ISEV standards ✔ EM EV Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH EV Cytosolic markers ✘ EV Membrane markers ✔ HSP90B1 EV Negative markers ✔ qNano EV Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for SIRT2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 TUBB   Biochemical Activity Homo sapiens 2 HDAC6 10013 Affinity Capture-MS Homo sapiens 3 ELL   Affinity Capture-MS Homo sapiens 4 PHB2 11331 Affinity Capture-MS Homo sapiens 5 SPOP   Affinity Capture-MS Homo sapiens 6 SARS 6301 Affinity Capture-MS Homo sapiens 7 SIRT2 22933 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 KRT78 196374 Affinity Capture-MS Homo sapiens 9 GYS1 2997 Affinity Capture-MS Homo sapiens 10 RTN4 57142 Affinity Capture-MS Homo sapiens View the network

Pathways in which SIRT2 is involved

No pathways found