Gene description for CST5
Gene name cystatin D
Gene symbol CST5
Other names/aliases -
Species Homo sapiens
 Database cross references - CST5
ExoCarta ExoCarta_1473
Vesiclepedia VP_1473
Entrez Gene 1473
HGNC 2477
MIM 123858
UniProt P28325  
 CST5 identified in sEVs derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for CST5
Molecular Function
    cysteine-type endopeptidase inhibitor activity GO:0004869 IBA
    cysteine-type endopeptidase inhibitor activity GO:0004869 IDA
    protein binding GO:0005515 IPI
Subcellular Localization
    extracellular region GO:0005576 IDA
    extracellular space GO:0005615 IBA
    cytoplasm GO:0005737 IBA
    vesicle GO:0031982 IBA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified CST5 in sEVs
1
Experiment ID 66
MISEV standards
IEM
Biophysical techniques
TSG101|Alix|CD63|CD81
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for CST5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ENDOG  
Affinity Capture-MS Homo sapiens
2 HSPA13 6782
Affinity Capture-MS Homo sapiens
3 PLEKHG6  
Affinity Capture-MS Homo sapiens
4 HS3ST1  
Affinity Capture-MS Homo sapiens
5 HKDC1 80201
Affinity Capture-MS Homo sapiens
6 CRH  
Affinity Capture-MS Homo sapiens
7 MCAM 4162
Affinity Capture-MS Homo sapiens
8 RPP25L  
Affinity Capture-MS Homo sapiens
9 BTD 686
Affinity Capture-MS Homo sapiens
10 FKBP15 23307
Affinity Capture-MS Homo sapiens
11 TENM3 55714
Affinity Capture-MS Homo sapiens
12 ARSB 411
Affinity Capture-MS Homo sapiens
13 TIMM10  
Affinity Capture-MS Homo sapiens
14 BCHE 590
Affinity Capture-MS Homo sapiens
15 TMEM67 91147
Affinity Capture-MS Homo sapiens
16 UBR3  
Affinity Capture-MS Homo sapiens
17 SNRPF 6636
Affinity Capture-MS Homo sapiens
18 IL20  
Affinity Capture-MS Homo sapiens
19 GDF15 9518
Affinity Capture-MS Homo sapiens
20 HBQ1  
Affinity Capture-MS Homo sapiens
21 KIR2DS2  
Affinity Capture-MS Homo sapiens
22 PARK2  
Affinity Capture-MS Homo sapiens
23 VWDE  
Affinity Capture-MS Homo sapiens
24 FRMD1  
Affinity Capture-MS Homo sapiens
25 BTBD1  
Affinity Capture-MS Homo sapiens
26 ZNF491  
Affinity Capture-MS Homo sapiens
27 PCK1 5105
Affinity Capture-MS Homo sapiens
28 HINT2 84681
Affinity Capture-MS Homo sapiens
29 RHOBTB1  
Affinity Capture-MS Homo sapiens
30 CTSS 1520
Reconstituted Complex Homo sapiens
31 SIRT2 22933
Affinity Capture-MS Homo sapiens
32 ZER1 10444
Affinity Capture-MS Homo sapiens
33 ARSK  
Affinity Capture-MS Homo sapiens
34 RCAN1  
Affinity Capture-MS Homo sapiens
35 CTSH 1512
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CST5 is involved
No pathways found





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