Gene description for CST5
Gene name cystatin D
Gene symbol CST5
Other names/aliases -
Species Homo sapiens
 Database cross references - CST5
ExoCarta ExoCarta_1473
Entrez Gene 1473
HGNC 2477
MIM 123858
UniProt P28325  
 CST5 identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for CST5
Molecular Function
    cysteine-type endopeptidase inhibitor activity GO:0004869 IDA
    protein binding GO:0005515 IPI
Biological Process
    negative regulation of endopeptidase activity GO:0010951 TAS
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    extracellular region GO:0005576 IDA
 Experiment description of studies that identified CST5 in exosomes
1
Experiment ID 66
ISEV standards
IEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD63|CD81
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for CST5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CTSS  
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which CST5 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here