Gene description for FKBP15
Gene name FK506 binding protein 15, 133kDa
Gene symbol FKBP15
Other names/aliases FKBP133
KIAA0674
PPP1R76
Species Homo sapiens
 Database cross references - FKBP15
ExoCarta ExoCarta_23307
Entrez Gene 23307
HGNC 23397
UniProt Q5T1M5  
 FKBP15 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for FKBP15
Molecular Function
    actin binding GO:0003779 IEA
    protein binding GO:0005515 IPI
Biological Process
    endocytosis GO:0006897 IEA
    protein folding GO:0006457 IEA
    negative regulation of phosphatase activity GO:0010923 IDA
Subcellular Localization
    axon GO:0030424 IEA
    membrane GO:0016020 IDA
    actin filament GO:0005884 IEA
    growth cone GO:0030426 IEA
    early endosome GO:0005769 IEA
 Experiment description of studies that identified FKBP15 in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FKBP15
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FKBP15 is involved
No pathways found





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