Gene description for CDK19
Gene name cyclin-dependent kinase 19
Gene symbol CDK19
Other names/aliases CDC2L6
CDK11
bA346C16.3
Species Homo sapiens
 Database cross references - CDK19
ExoCarta ExoCarta_23097
Vesiclepedia VP_23097
Entrez Gene 23097
HGNC 19338
MIM 614720
UniProt Q9BWU1  
 CDK19 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for CDK19
Molecular Function
    ATP binding GO:0005524 IEA
    cyclin-dependent protein serine/threonine kinase activity GO:0004693 IEA
Biological Process
    protein phosphorylation GO:0006468 IEA
    regulation of cell cycle GO:0051726 IEA
 Experiment description of studies that identified CDK19 in exosomes
1
Experiment ID 488
MISEV standards
EM
EV Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
CANX
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for CDK19
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MED29  
Affinity Capture-MS Homo sapiens
2 MED9  
Affinity Capture-MS Homo sapiens
3 MED10  
Affinity Capture-MS Homo sapiens
4 MYCBPAP 84073
Affinity Capture-MS Homo sapiens
5 RB1CC1 9821
Affinity Capture-MS Homo sapiens
6 MED17  
Affinity Capture-MS Homo sapiens
7 SRSF7 6432
Invivo Homo sapiens
8 MED19  
Affinity Capture-MS Homo sapiens
9 MED28  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CDK19 is involved
PathwayEvidenceSource
PPARA activates gene expression TAS Reactome
Transcriptional regulation of white adipocyte differentiation TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here