Gene description for CUTA
Gene name cutA divalent cation tolerance homolog (E. coli)
Gene symbol CUTA
Other names/aliases ACHAP
C6orf82
Species Homo sapiens
 Database cross references - CUTA
ExoCarta ExoCarta_51596
Entrez Gene 51596
HGNC 21101
UniProt O60888  
 CUTA identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
Urine 19056867    
 Gene ontology annotations for CUTA
Molecular Function
    protein binding GO:0005515 IPI
    enzyme binding GO:0019899 IPI
Biological Process
    protein localization GO:0008104 IDA
    response to metal ion GO:0010038 IEA
Subcellular Localization
    membrane GO:0016020 IDA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified CUTA in exosomes
1
Experiment ID 191
ISEV standards
EV Biophysical techniques
Alix
EV Cytosolic markers
CD81|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for CUTA
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CUTA is involved
No pathways found





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