Gene description for DLD
Gene name dihydrolipoamide dehydrogenase
Gene symbol DLD
Other names/aliases DLDD
DLDH
E3
GCSL
LAD
PHE3
Species Homo sapiens
 Database cross references - DLD
ExoCarta ExoCarta_1738
Vesiclepedia VP_1738
Entrez Gene 1738
HGNC 2898
MIM 238331
UniProt P09622  
 DLD identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 19415654    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for DLD
Molecular Function
    dihydrolipoyl dehydrogenase activity GO:0004148 IBA
    dihydrolipoyl dehydrogenase activity GO:0004148 IDA
    protein binding GO:0005515 IPI
    pyruvate dehydrogenase (NAD+) activity GO:0034604 IDA
    branched-chain alpha-keto acid dehydrogenase activity GO:0047101 IDA
    flavin adenine dinucleotide binding GO:0050660 IBA
Biological Process
    acetyl-CoA biosynthetic process from pyruvate GO:0006086 IC
    acetyl-CoA biosynthetic process from pyruvate GO:0006086 IDA
    acetyl-CoA biosynthetic process from pyruvate GO:0006086 ISS
    pyruvate metabolic process GO:0006090 IBA
    2-oxoglutarate metabolic process GO:0006103 IBA
    mitochondrial electron transport, NADH to ubiquinone GO:0006120 IEA
    proteolysis GO:0006508 IEA
    gastrulation GO:0007369 IEA
    branched-chain amino acid catabolic process GO:0009083 IDA
    regulation of membrane potential GO:0042391 IEA
    sperm capacitation GO:0048240 IEA
Subcellular Localization
    nucleus GO:0005634 IDA
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrion GO:0005739 NAS
    mitochondrial matrix GO:0005759 NAS
    mitochondrial matrix GO:0005759 TAS
    motile cilium GO:0031514 IEA
    acrosomal matrix GO:0043159 IEA
    oxoglutarate dehydrogenase complex GO:0045252 IBA
    oxoglutarate dehydrogenase complex GO:0045252 IDA
    pyruvate dehydrogenase complex GO:0045254 IDA
    pyruvate dehydrogenase complex GO:0045254 IPI
    pyruvate dehydrogenase complex GO:0045254 ISS
    branched-chain alpha-ketoacid dehydrogenase complex GO:0160157 IDA
    branched-chain alpha-ketoacid dehydrogenase complex GO:0160157 IPI
    oxoadipate dehydrogenase complex GO:0160167 IDA
    acetyltransferase complex GO:1902493 IEA
 Experiment description of studies that identified DLD in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 65
MISEV standards
✘ Biophysical techniques
✔
HSP60|HSP27|GAPDH|FLOT2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19415654    
Organism Homo sapiens
Experiment description Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7.
Authors "Staubach S, Razawi H, Hanisch FG."
Journal name PROTEOMICS
Publication year 2009
Sample Breast cancer cells
Sample name MCF-7
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
6
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
8
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 219
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name C666-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 220
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP69
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 221
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP460
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 193
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
PHB
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
33
Experiment ID 194
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 195
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DLD
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF3A 8661
Affinity Capture-MS Homo sapiens
2 HDLBP 3069
Affinity Capture-MS Homo sapiens
3 MCM6 4175
Affinity Capture-MS Homo sapiens
4 MACROD1 28992
Affinity Capture-MS Homo sapiens
5 STAT5B 6777
Affinity Capture-MS Homo sapiens
6 EIF3C 8663
Affinity Capture-MS Homo sapiens
7 LDHB 3945
Affinity Capture-MS Homo sapiens
8 EIF2B2 8892
Affinity Capture-MS Homo sapiens
9 CAP1 10487
Affinity Capture-MS Homo sapiens
10 UBA1 7317
Affinity Capture-MS Homo sapiens
11 SMARCE1 6605
Affinity Capture-MS Homo sapiens
12 RPL12 6136
Affinity Capture-MS Homo sapiens
13 PARK7 11315
Affinity Capture-MS Homo sapiens
14 SEPT2 4735
Affinity Capture-MS Homo sapiens
15 PCBP3 54039
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 CKB 1152
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
17 TMPRSS7  
Cross-Linking-MS (XL-MS) Homo sapiens
18 DDX23 9416
Affinity Capture-MS Homo sapiens
19 WDR76  
Affinity Capture-MS Homo sapiens
20 DARS 1615
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
21 ISYNA1 51477
Co-fractionation Homo sapiens
22 UBE2K 3093
Affinity Capture-MS Homo sapiens
23 MRPS36 92259
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
24 H2AFV 94239
Affinity Capture-MS Homo sapiens
25 HSPH1 10808
Affinity Capture-MS Homo sapiens
26 ETFA 2108
Affinity Capture-MS Homo sapiens
27 THRAP3 9967
Affinity Capture-MS Homo sapiens
28 DYNLL1 8655
Affinity Capture-MS Homo sapiens
29 CHORDC1 26973
Affinity Capture-MS Homo sapiens
30 FAM98B 283742
Affinity Capture-MS Homo sapiens
31 POLR2C 5432
Affinity Capture-MS Homo sapiens
32 NONO 4841
Co-fractionation Homo sapiens
33 CTNNA1 1495
Affinity Capture-MS Homo sapiens
34 BTRC 8945
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 AP1S2 8905
Affinity Capture-MS Homo sapiens
36 FARSA 2193
Affinity Capture-MS Homo sapiens
37 ANXA7 310
Affinity Capture-MS Homo sapiens
38 MAP1B 4131
Cross-Linking-MS (XL-MS) Homo sapiens
39 TNFAIP8 25816
Co-fractionation Homo sapiens
40 PABPC1 26986
Affinity Capture-MS Homo sapiens
41 EEF1E1 9521
Affinity Capture-MS Homo sapiens
42 NUDC 10726
Affinity Capture-MS Homo sapiens
43 TYK2 7297
Co-fractionation Homo sapiens
44 ACTN4 81
Affinity Capture-MS Homo sapiens
45 OGT 8473
Reconstituted Complex Homo sapiens
46 GORASP2 26003
Co-fractionation Homo sapiens
47 NAA10 8260
Affinity Capture-MS Homo sapiens
48 BANF1 8815
Affinity Capture-MS Homo sapiens
49 YWHAQ 10971
Affinity Capture-MS Homo sapiens
50 HECTD1 25831
Affinity Capture-MS Homo sapiens
51 DDX39B 7919
Affinity Capture-MS Homo sapiens
52 SND1 27044
Affinity Capture-MS Homo sapiens
53 CACYBP 27101
Affinity Capture-MS Homo sapiens
54 CD3EAP  
Affinity Capture-MS Homo sapiens
55 BCLAF1 9774
Affinity Capture-MS Homo sapiens
56 EIF3G 8666
Affinity Capture-MS Homo sapiens
57 TMPO 7112
Affinity Capture-MS Homo sapiens
58 CSTF1 1477
Co-fractionation Homo sapiens
59 HTRA2 27429
Co-fractionation Homo sapiens
60 DAP3 7818
Affinity Capture-MS Homo sapiens
61 DOCK8 81704
Affinity Capture-MS Homo sapiens
62 PITRM1 10531
Co-fractionation Homo sapiens
63 SDHA 6389
Co-fractionation Homo sapiens
64 SIRT7  
Affinity Capture-MS Homo sapiens
65 GGH 8836
Co-fractionation Homo sapiens
66 ASS1 445
Co-fractionation Homo sapiens
67 YWHAZ 7534
Affinity Capture-MS Homo sapiens
68 ATP1B3 483
Co-fractionation Homo sapiens
69 EEF1B2 1933
Affinity Capture-MS Homo sapiens
70 RBBP4 5928
Affinity Capture-MS Homo sapiens
71 FN1 2335
Affinity Capture-MS Homo sapiens
72 CDC42 998
Affinity Capture-MS Homo sapiens
73 STRAP 11171
Affinity Capture-MS Homo sapiens
74 SOAT1 6646
Affinity Capture-MS Homo sapiens
75 IST1 9798
Affinity Capture-MS Homo sapiens
76 RPA3 6119
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 NME1 4830
Co-fractionation Homo sapiens
78 FH 2271
Co-fractionation Homo sapiens
79 DLST 1743
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
80 TSFM 10102
Affinity Capture-MS Homo sapiens
81 HSPA4 3308
Affinity Capture-MS Homo sapiens
82 PSMC5 5705
Affinity Capture-MS Homo sapiens
83 EIF2B1 1967
Affinity Capture-MS Homo sapiens
84 SCPEP1 59342
Co-fractionation Homo sapiens
85 DLAT 1737
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
86 SUPT16H 11198
Affinity Capture-MS Homo sapiens
87 CUTA 51596
Co-fractionation Homo sapiens
88 NUDT21 11051
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
89 FASN 2194
Affinity Capture-MS Homo sapiens
90 COPZ1 22818
Affinity Capture-MS Homo sapiens
91 EIF3I 8668
Affinity Capture-MS Homo sapiens
92 RUVBL2 10856
Affinity Capture-MS Homo sapiens
93 PCMT1 5110
Affinity Capture-MS Homo sapiens
94 SUCLG2 8801
Co-fractionation Homo sapiens
95 FBXO21  
Affinity Capture-MS Homo sapiens
96 CDC37 11140
Affinity Capture-MS Homo sapiens
97 HIST1H2BC 8347
Affinity Capture-MS Homo sapiens
98 SKP1 6500
Affinity Capture-MS Homo sapiens
99 APRT 353
Affinity Capture-MS Homo sapiens
100 SMN2 6607
Affinity Capture-MS Homo sapiens
101 BOLA2 552900
Affinity Capture-MS Homo sapiens
102 OAT 4942
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
103 PARS2 25973
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 RAB11A 8766
Affinity Capture-MS Homo sapiens
105 REXO2 25996
Co-fractionation Homo sapiens
106 PTGES3 10728
Affinity Capture-MS Homo sapiens
107 RAB5C 5878
Affinity Capture-MS Homo sapiens
108 PSMC4 5704
Affinity Capture-MS Homo sapiens
109 RANGAP1 5905
Affinity Capture-MS Homo sapiens
110 PSMD3 5709
Affinity Capture-MS Homo sapiens
111 GSTP1 2950
Affinity Capture-MS Homo sapiens
112 LDHA 3939
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
113 MCM3 4172
Affinity Capture-MS Homo sapiens
114 SMC3 9126
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
115 HIST1H2BE 8344
Affinity Capture-MS Homo sapiens
116 ANP32A 8125
Affinity Capture-MS Homo sapiens
117 SIAH2 6478
Affinity Capture-MS Homo sapiens
118 ARHGAP39  
Affinity Capture-MS Homo sapiens
119 EIF3K 27335
Affinity Capture-MS Homo sapiens
120 FMR1 2332
Affinity Capture-MS Homo sapiens
121 RPA2 6118
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 NACA 4666
Affinity Capture-MS Homo sapiens
123 HIST1H2BG 8339
Affinity Capture-MS Homo sapiens
124 YARS 8565
Affinity Capture-MS Homo sapiens
125 NDUFB5 4711
Co-fractionation Homo sapiens
126 RNMT 8731
Co-fractionation Homo sapiens
127 CLTB 1212
Affinity Capture-MS Homo sapiens
128 COPA 1314
Affinity Capture-MS Homo sapiens
129 NDUFS2 4720
Co-fractionation Homo sapiens
130 OGDH 4967
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
131 RBMXL2  
Affinity Capture-MS Homo sapiens
132 NOLC1 9221
Affinity Capture-MS Homo sapiens
133 H1FX 8971
Affinity Capture-MS Homo sapiens
134 PDHB 5162
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
135 ACTR1A 10121
Affinity Capture-MS Homo sapiens
136 CTH 1491
Co-fractionation Homo sapiens
137 PRDX2 7001
Affinity Capture-MS Homo sapiens
138 STIP1 10963
Co-fractionation Homo sapiens
139 LACTB 114294
Co-fractionation Homo sapiens
140 YWHAH 7533
Affinity Capture-MS Homo sapiens
141 AASDHPPT 60496
Affinity Capture-MS Homo sapiens
142 TOMM40 10452
Co-fractionation Homo sapiens
143 FBL 2091
Affinity Capture-MS Homo sapiens
144 PFN2 5217
Affinity Capture-MS Homo sapiens
145 HSD17B4 3295
Affinity Capture-MS Homo sapiens
146 PLS3 5358
Affinity Capture-MS Homo sapiens
147 YWHAB 7529
Affinity Capture-MS Homo sapiens
148 CCT2 10576
Affinity Capture-MS Homo sapiens
149 PFN1 5216
Affinity Capture-MS Homo sapiens
150 MRPS35 60488
Affinity Capture-MS Homo sapiens
151 HNRNPA0 10949
Co-fractionation Homo sapiens
152 TTC4  
Affinity Capture-MS Homo sapiens
153 PNN 5411
Affinity Capture-MS Homo sapiens
154 UBAP2L 9898
Affinity Capture-MS Homo sapiens
155 ACIN1 22985
Affinity Capture-MS Homo sapiens
156 CSTF3 1479
Affinity Capture-MS Homo sapiens
157 PDHX 8050
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
158 S100A8 6279
Affinity Capture-MS Homo sapiens
159 UQCRC1 7384
Co-fractionation Homo sapiens
160 HIST1H2BF 8343
Affinity Capture-MS Homo sapiens
161 IARS 3376
Affinity Capture-MS Homo sapiens
162 COPS7B 64708
Affinity Capture-MS Homo sapiens
163 PPM1G 5496
Affinity Capture-MS Homo sapiens
164 AIMP2 7965
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
165 CARS 833
Co-fractionation Homo sapiens
166 RSL1D1 26156
Affinity Capture-MS Homo sapiens
167 COLGALT1 79709
Co-fractionation Homo sapiens
168 Rbm14  
Two-hybrid Mus musculus
169 AIFM1 9131
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
170 XPO1 7514
Co-fractionation Homo sapiens
171 UBAP2 55833
Co-fractionation Homo sapiens
172 PPA1 5464
Affinity Capture-MS Homo sapiens
173 PRKAR2A 5576
Affinity Capture-MS Homo sapiens
174 MRPL9 65005
Co-fractionation Homo sapiens
175 HSD17B10 3028
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
176 HOOK3 84376
Proximity Label-MS Homo sapiens
177 FUS 2521
Affinity Capture-MS Homo sapiens
178 LARS 51520
Affinity Capture-MS Homo sapiens
179 DHTKD1 55526
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
180 TPM1 7168
Affinity Capture-MS Homo sapiens
181 PPP2R1A 5518
Affinity Capture-MS Homo sapiens
182 BAG1 573
Affinity Capture-MS Homo sapiens
183 DYNC1LI1 51143
Affinity Capture-MS Homo sapiens
184 SET 6418
Affinity Capture-MS Homo sapiens
185 SNX12 29934
Co-fractionation Homo sapiens
186 HPRT1 3251
Affinity Capture-MS Homo sapiens
187 DDRGK1 65992
Affinity Capture-MS Homo sapiens
188 PGAM1 5223
Affinity Capture-MS Homo sapiens
189 ADRM1 11047
Affinity Capture-MS Homo sapiens
190 HUWE1 10075
Affinity Capture-MS Homo sapiens
191 PHGDH 26227
Affinity Capture-MS Homo sapiens
192 DSP 1832
Affinity Capture-MS Homo sapiens
193 GSR 2936
Co-fractionation Homo sapiens
194 AP3S1 1176
Affinity Capture-MS Homo sapiens
195 GATAD2A 54815
Affinity Capture-MS Homo sapiens
196 UCK2 7371
Affinity Capture-MS Homo sapiens
197 CS 1431
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
198 EIF3F 8665
Affinity Capture-MS Homo sapiens
199 HNRNPH2 3188
Co-fractionation Homo sapiens
200 ATXN3 4287
Affinity Capture-MS Homo sapiens
201 PDCD6IP 10015
Affinity Capture-MS Homo sapiens
202 HDAC6 10013
Affinity Capture-MS Homo sapiens
203 BCKDHA 593
Co-fractionation Homo sapiens
204 PBDC1 51260
Affinity Capture-MS Homo sapiens
205 HLTF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
206 CXCL14  
Affinity Capture-MS Homo sapiens
207 DSC1 1823
Affinity Capture-MS Homo sapiens
208 COX8A  
Proximity Label-MS Homo sapiens
209 STK26 51765
Affinity Capture-MS Homo sapiens
210 OTUB1 55611
Affinity Capture-MS Homo sapiens
211 SHMT2 6472
Affinity Capture-MS Homo sapiens
212 BUB3 9184
Affinity Capture-MS Homo sapiens
213 UCHL3 7347
Co-fractionation Homo sapiens
214 CDK1 983
Affinity Capture-MS Homo sapiens
215 DCD 117159
Affinity Capture-MS Homo sapiens
216 BCL2L13 23786
Co-fractionation Homo sapiens
217 EEF1D 1936
Affinity Capture-MS Homo sapiens
218 ARF1 375
Affinity Capture-MS Homo sapiens
219 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
220 KRAS 3845
Negative Genetic Homo sapiens
221 TIMM13 26517
Affinity Capture-MS Homo sapiens
222 IDH3A 3419
Affinity Capture-MS Homo sapiens
223 RAB1A 5861
Affinity Capture-MS Homo sapiens
224 EEF1G 1937
Affinity Capture-MS Homo sapiens
225 SORL1 6653
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
226 PTMA 5757
Affinity Capture-MS Homo sapiens
227 YWHAE 7531
Affinity Capture-MS Homo sapiens
228 GATA2  
Affinity Capture-MS Homo sapiens
229 BOLA2B 654483
Affinity Capture-MS Homo sapiens
230 ARCN1 372
Affinity Capture-MS Homo sapiens
231 PSMD10 5716
Affinity Capture-MS Homo sapiens
232 C7orf55  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
233 CAPZB 832
Co-fractionation Homo sapiens
234 RPL10A 4736
Affinity Capture-MS Homo sapiens
235 RUVBL1 8607
Affinity Capture-MS Homo sapiens
236 TRIM28 10155
Affinity Capture-MS Homo sapiens
237 NDUFS3 4722
Affinity Capture-MS Homo sapiens
238 DYNC1LI2 1783
Proximity Label-MS Homo sapiens
239 SDHB 6390
Co-fractionation Homo sapiens
240 EIF3B 8662
Affinity Capture-MS Homo sapiens
241 MAP2K2 5605
Affinity Capture-MS Homo sapiens
242 PGD 5226
Co-fractionation Homo sapiens
243 PDIA6 10130
Affinity Capture-MS Homo sapiens
244 GART 2618
Affinity Capture-MS Homo sapiens
245 LDHAL6A  
Affinity Capture-MS Homo sapiens
246 TFCP2 7024
Affinity Capture-MS Homo sapiens
247 CSNK2B 1460
Affinity Capture-MS Homo sapiens
248 EHD1 10938
Affinity Capture-MS Homo sapiens
249 FEN1 2237
Affinity Capture-MS Homo sapiens
250 PSME3 10197
Affinity Capture-MS Homo sapiens
251 RPL27 6155
Affinity Capture-MS Homo sapiens
252 IRS4 8471
Affinity Capture-MS Homo sapiens
253 SUCLG1 8802
Co-fractionation Homo sapiens
254 PARK2  
Affinity Capture-MS Homo sapiens
255 COPE 11316
Affinity Capture-MS Homo sapiens
256 SRRT 51593
Affinity Capture-MS Homo sapiens
257 DIABLO 56616
Affinity Capture-MS Homo sapiens
258 PLOD2 5352
Co-fractionation Homo sapiens
259 NTRK1 4914
Affinity Capture-MS Homo sapiens
260 DNAJA1 3301
Affinity Capture-MS Homo sapiens
261 MRPL11 65003
Co-fractionation Homo sapiens
262 SLX4IP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
263 YAP1 10413
Affinity Capture-MS Homo sapiens
264 AIMP1 9255
Affinity Capture-MS Homo sapiens
265 CREG1 8804
Co-fractionation Homo sapiens
266 LARP1 23367
Affinity Capture-MS Homo sapiens
267 HNRNPDL 9987
Co-fractionation Homo sapiens
268 UBE2S  
Affinity Capture-MS Homo sapiens
269 ACAT1 38
Co-fractionation Homo sapiens
270 OLA1 29789
Affinity Capture-MS Homo sapiens
271 AK2 204
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
272 TRMT10C 54931
Affinity Capture-MS Homo sapiens
273 BAG2 9532
Affinity Capture-MS Homo sapiens
274 SAR1A 56681
Affinity Capture-MS Homo sapiens
275 EEF2 1938
Affinity Capture-MS Homo sapiens
276 ATXN10 25814
Affinity Capture-MS Homo sapiens
277 PRPF19 27339
Affinity Capture-MS Homo sapiens
278 PSPC1 55269
Affinity Capture-MS Homo sapiens
279 HSDL2 84263
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
280 NHP2L1 4809
Affinity Capture-MS Homo sapiens
281 CFL2 1073
Co-fractionation Homo sapiens
282 PPP6C 5537
Affinity Capture-MS Homo sapiens
283 HYOU1 10525
Affinity Capture-MS Homo sapiens
284 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
285 SEPT7 989
Affinity Capture-MS Homo sapiens
286 HIST1H2BI 8346
Affinity Capture-MS Homo sapiens
287 XRCC5 7520
Affinity Capture-MS Homo sapiens
288 DBT 1629
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
289 DNAJC4  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
290 EIF2S1 1965
Affinity Capture-MS Homo sapiens
291 MTHFD2 10797
Affinity Capture-MS Homo sapiens
292 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
293 FBXW11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
294 ALDOC 230
Co-fractionation Homo sapiens
295 CCT8 10694
Affinity Capture-MS Homo sapiens
296 SOD2 6648
Co-fractionation Homo sapiens
297 SMN1 6606
Affinity Capture-MS Homo sapiens
298 JUP 3728
Affinity Capture-MS Homo sapiens
299 PDK3 5165
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
300 RPA1 6117
Affinity Capture-MS Homo sapiens
301 PDHA1 5160
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
302 G3BP1 10146
Affinity Capture-MS Homo sapiens
303 MTHFD1 4522
Affinity Capture-MS Homo sapiens
304 OTUD6B 51633
Co-fractionation Homo sapiens
305 CCT7 10574
Affinity Capture-MS Homo sapiens
306 TRAP1 10131
Affinity Capture-MS Homo sapiens
307 UFL1 23376
Affinity Capture-MS Homo sapiens
308 MIF 4282
Affinity Capture-MS Homo sapiens
309 MRPS18B 28973
Affinity Capture-MS Homo sapiens
310 API5 8539
Affinity Capture-MS Homo sapiens
311 AARS2  
Proximity Label-MS Homo sapiens
312 ABHD10 55347
Affinity Capture-MS Homo sapiens
313 RTCB 51493
Affinity Capture-MS Homo sapiens
314 PRDX6 9588
Affinity Capture-MS Homo sapiens
315 MGME1  
Affinity Capture-MS Homo sapiens
316 C14orf166 51637
Affinity Capture-MS Homo sapiens
317 SERBP1 26135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
318 SNX2 6643
Affinity Capture-MS Homo sapiens
319 ARHGAP24  
Affinity Capture-MS Homo sapiens
320 MRPS22 56945
Affinity Capture-MS Homo sapiens
321 COPS4 51138
Affinity Capture-MS Homo sapiens
322 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
323 ATG3 64422
Affinity Capture-MS Homo sapiens
324 SIAH1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
325 UBE2H 7328
Affinity Capture-MS Homo sapiens
326 QARS 5859
Affinity Capture-MS Homo sapiens
327 PSMD6 9861
Affinity Capture-MS Homo sapiens
328 PTBP1 5725
Affinity Capture-MS Homo sapiens
329 RPL30 6156
Affinity Capture-MS Homo sapiens
330 PSMD11 5717
Affinity Capture-MS Homo sapiens
331 UBE2M 9040
Affinity Capture-MS Homo sapiens
332 KPNB1 3837
Affinity Capture-MS Homo sapiens
333 SUB1 10923
Affinity Capture-MS Homo sapiens
334 PAICS 10606
Affinity Capture-MS Homo sapiens
335 MRPL37 51253
Co-fractionation Homo sapiens
336 ETFB 2109
Co-fractionation Homo sapiens
337 ECI1 1632
Co-fractionation Homo sapiens
338 ELAVL1 1994
Affinity Capture-MS Homo sapiens
339 CCDC124 115098
Affinity Capture-MS Homo sapiens
340 ILF2 3608
Affinity Capture-MS Homo sapiens
341 PSMD2 5708
Affinity Capture-MS Homo sapiens
342 HIST1H2BD 3017
Affinity Capture-MS Homo sapiens
343 PRDX3 10935
Affinity Capture-MS Homo sapiens
344 PITPNB 23760
Affinity Capture-MS Homo sapiens
345 INIP  
Affinity Capture-MS Homo sapiens
346 MRPL23 6150
Co-fractionation Homo sapiens
347 ELP2 55250
Affinity Capture-MS Homo sapiens
348 MDH1 4190
Co-fractionation Homo sapiens
349 YWHAG 7532
Affinity Capture-MS Homo sapiens
350 C21orf33  
Affinity Capture-MS Homo sapiens
351 PRPS1 5631
Affinity Capture-MS Homo sapiens
352 MAP7D3 79649
Co-fractionation Homo sapiens
353 SERPINH1 871
Affinity Capture-MS Homo sapiens
354 PEPD 5184
Co-fractionation Homo sapiens
355 VAT1 10493
Affinity Capture-MS Homo sapiens
356 NME2 4831
Co-fractionation Homo sapiens
357 PSMC6 5706
Affinity Capture-MS Homo sapiens
358 PSMC3 5702
Affinity Capture-MS Homo sapiens
359 NFU1 27247
Co-fractionation Homo sapiens
360 STOML2 30968
Affinity Capture-MS Homo sapiens
361 RB1 5925
Co-fractionation Homo sapiens
362 MRPL13  
Co-fractionation Homo sapiens
363 PPP1CA 5499
Affinity Capture-MS Homo sapiens
364 RBBP7 5931
Affinity Capture-MS Homo sapiens
365 NAA50 80218
Affinity Capture-MS Homo sapiens
366 PSMD4 5710
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
367 HSP90B1 7184
Affinity Capture-MS Homo sapiens
368 PSMC1 5700
Affinity Capture-MS Homo sapiens
369 DTYMK 1841
Affinity Capture-MS Homo sapiens
370 ATF2  
Affinity Capture-MS Homo sapiens
371 VCP 7415
Affinity Capture-MS Homo sapiens
372 AP1B1 162
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
373 SF3B6 51639
Affinity Capture-MS Homo sapiens
374 DDX1 1653
Affinity Capture-MS Homo sapiens
375 H2AFY 9555
Affinity Capture-MS Homo sapiens
376 HIST1H2AB 8335
Affinity Capture-MS Homo sapiens
377 ACBD3 64746
Affinity Capture-MS Homo sapiens
378 ENO3 2027
Affinity Capture-MS Homo sapiens
379 MAT2A 4144
Affinity Capture-MS Homo sapiens
380 SNX1 6642
Affinity Capture-MS Homo sapiens
381 NFKBIE  
Affinity Capture-MS Homo sapiens
382 ACTN1 87
Affinity Capture-MS Homo sapiens
383 UBE2N 7334
Affinity Capture-MS Homo sapiens
384 CDK9 1025
Affinity Capture-MS Homo sapiens
385 POLR2H 5437
Affinity Capture-MS Homo sapiens
386 ASB15 142685
Affinity Capture-MS Homo sapiens
387 SLC2A4  
Affinity Capture-MS Homo sapiens
388 NDUFA9 4704
Co-fractionation Homo sapiens
389 EIF4G1 1981
Affinity Capture-MS Homo sapiens
390 PSMD13 5719
Affinity Capture-MS Homo sapiens
391 UQCRC2 7385
Co-fractionation Homo sapiens
392 KCTD12 115207
Affinity Capture-MS Homo sapiens
393 COPS8 10920
Affinity Capture-MS Homo sapiens
394 NFS1 9054
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
395 AP1M1 8907
Affinity Capture-MS Homo sapiens
396 ETF1 2107
Affinity Capture-MS Homo sapiens
397 SEC23A 10484
Affinity Capture-MS Homo sapiens
398 MCM4 4173
Affinity Capture-MS Homo sapiens
399 NAP1L1 4673
Affinity Capture-MS Homo sapiens
400 PYCR2 29920
Affinity Capture-MS Homo sapiens
401 PSMD7 5713
Affinity Capture-MS Homo sapiens
402 ECHS1 1892
Affinity Capture-MS Homo sapiens
403 DKC1 1736
Affinity Capture-MS Homo sapiens
404 GALK1 2584
Affinity Capture-MS Homo sapiens
405 ATP1B1 481
Co-fractionation Homo sapiens
406 EPRS 2058
Affinity Capture-MS Homo sapiens
407 TWF1 5756
Affinity Capture-MS Homo sapiens
408 FSCN1 6624
Affinity Capture-MS Homo sapiens
409 C9orf72  
Affinity Capture-MS Homo sapiens
410 DCTPP1 79077
Affinity Capture-MS Homo sapiens
411 EIF3D 8664
Affinity Capture-MS Homo sapiens
412 AK4 205
Affinity Capture-MS Homo sapiens
413 DPP3 10072
Co-fractionation Homo sapiens
414 MRPL42  
Co-fractionation Homo sapiens
415 ACP1 52
Affinity Capture-MS Homo sapiens
416 PDCL3 79031
Affinity Capture-MS Homo sapiens
417 PAFAH1B3 5050
Affinity Capture-MS Homo sapiens
418 CPSF6 11052
Affinity Capture-MS Homo sapiens
419 ERH 2079
Affinity Capture-MS Homo sapiens
420 DNAJA2 10294
Affinity Capture-MS Homo sapiens
421 POLR1C 9533
Affinity Capture-MS Homo sapiens
422 MRPS31  
Affinity Capture-MS Homo sapiens
423 HNRNPA2B1 3181
Co-fractionation Homo sapiens
424 SRP72 6731
Affinity Capture-MS Homo sapiens
425 VTA1 51534
Co-fractionation Homo sapiens
426 SUCLA2 8803
Co-fractionation Homo sapiens
427 EIF4A3 9775
Affinity Capture-MS Homo sapiens
428 Hdac6  
Affinity Capture-MS Mus musculus
429 ARF4 378
Affinity Capture-MS Homo sapiens
430 OGDHL  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
431 TF 7018
Co-fractionation Homo sapiens
432 TXN 7295
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
433 NEK2  
Cross-Linking-MS (XL-MS) Homo sapiens
434 RPL23 9349
Co-fractionation Homo sapiens
435 XRCC6 2547
Affinity Capture-MS Homo sapiens
436 RARS 5917
Affinity Capture-MS Homo sapiens
437 EIF3M 10480
Affinity Capture-MS Homo sapiens
438 UFM1 51569
Affinity Capture-MS Homo sapiens
439 CNDP2 55748
Co-fractionation Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here