Gene description for PSMD10
Gene name	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
Gene symbol	PSMD10
Other names/aliases	dJ889N15.2 p28 p28(GANK)
Species	Homo sapiens
Database cross references - PSMD10
ExoCarta	ExoCarta_5716
Entrez Gene	5716
HGNC	9555
MIM	300880
UniProt	O75832
PSMD10 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Squamous carcinoma cells	20124223
Thymus	23844026

Gene ontology annotations for PSMD10

Molecular Function     protein binding GO:0005515 IPI     transcription factor binding GO:0008134 IPI Biological Process     positive regulation of protein ubiquitination GO:0031398 IMP     protein polyubiquitination GO:0000209 TAS     small molecule metabolic process GO:0044281 TAS     cellular nitrogen compound metabolic process GO:0034641 TAS     negative regulation of MAPK cascade GO:0043409 IMP     positive regulation of canonical Wnt signaling pathway GO:0090263 TAS     gene expression GO:0010467 TAS     regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle GO:0051439 TAS     positive regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045737 IDA     negative regulation of NF-kappaB transcription factor activity GO:0032088 IDA     positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition GO:0051437 TAS     negative regulation of DNA damage response, signal transduction by p53 class mediator GO:0043518 IDA     apoptotic process GO:0006915 TAS     mitotic cell cycle GO:0000278 TAS     negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle GO:0051436 TAS     regulation of cellular amino acid metabolic process GO:0006521 TAS     stimulatory C-type lectin receptor signaling pathway GO:0002223 TAS     negative regulation of canonical Wnt signaling pathway GO:0090090 TAS     antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent GO:0002479 TAS     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IDA     cytoplasmic sequestering of NF-kappaB GO:0007253 IDA     innate immune response GO:0045087 TAS     antigen processing and presentation of exogenous peptide antigen via MHC class I GO:0042590 TAS     regulation of apoptotic process GO:0042981 TAS     anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 TAS     negative regulation of release of cytochrome c from mitochondria GO:0090201 IMP     programmed cell death GO:0012501 TAS     positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 TAS     negative regulation of apoptotic process GO:0043066 TAS     DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 TAS     proteasome regulatory particle assembly GO:0070682 IMP     viral process GO:0016032 TAS     antigen processing and presentation of peptide antigen via MHC class I GO:0002474 TAS     G1/S transition of mitotic cell cycle GO:0000082 TAS     positive regulation of cell growth GO:0030307 IDA Subcellular Localization     nucleus GO:0005634 IDA     proteasome complex GO:0000502 IDA     proteasome regulatory particle, base subcomplex GO:0008540 IDA     cytosol GO:0005829 TAS     cytoplasm GO:0005737 IDA     intermediate filament cytoskeleton GO:0045111 IDA     proteasome regulatory particle GO:0005838 TAS     nucleoplasm GO:0005654 TAS