Gene description for UBAP2L
Gene name ubiquitin associated protein 2-like
Gene symbol UBAP2L
Other names/aliases NICE-4
Species Homo sapiens
 Database cross references - UBAP2L
ExoCarta ExoCarta_9898
Entrez Gene 9898
HGNC 29877
UniProt Q14157  
 UBAP2L identified in exosomes derived from the following tissue/cell type
Prostate cancer cells 25844599    
 Gene ontology annotations for UBAP2L
Molecular Function
    protein binding GO:0005515 IPI
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    hematopoietic stem cell homeostasis GO:0061484 IGI
    binding of sperm to zona pellucida GO:0007339 IMP
Subcellular Localization
    PcG protein complex GO:0031519 IDA
    Ada2/Gcn5/Ada3 transcription activator complex GO:0005671 IDA
 Experiment description of studies that identified UBAP2L in exosomes
Experiment ID 275
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
 Protein-protein interactions for UBAP2L
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PRRC2A 7916
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which UBAP2L is involved
No pathways found

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