Gene description for ATXN10
Gene name ataxin 10
Gene symbol ATXN10
Other names/aliases E46L
HUMEEP
SCA10
Species Homo sapiens
 Database cross references - ATXN10
ExoCarta ExoCarta_25814
Entrez Gene 25814
HGNC 10549
MIM 611150
UniProt Q9UBB4  
 ATXN10 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for ATXN10
Molecular Function
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IEA
Biological Process
    nervous system development GO:0007399 IMP
    neuron projection development GO:0031175 IDA
Subcellular Localization
    extracellular space GO:0005615 IDA
    perinuclear region of cytoplasm GO:0048471 IDA
    neuronal cell body GO:0043025 IDA
    dendrite GO:0030425 IDA
    cytosol GO:0005829 IEA
    cytoplasm GO:0005737 IDA
    membrane GO:0016020 IDA
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified ATXN10 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ATXN10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GSTK1 373156
Affinity Capture-MS Homo sapiens
2 MAGED1  
Affinity Capture-MS Homo sapiens
3 BSG 682
Affinity Capture-MS Homo sapiens
4 DUSP24  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ATXN10 is involved
No pathways found





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